15 result(s) for 'PDL1'
11 - 15 of 15 results for 'PDL1'
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Introduction to immuno oncology
1. Introduction to Immuno-Oncology Michael Bates, MD Oncology Strategy, Medical and Scientific Affairs Cepheid Sunnyvale, CA Cepheid and Leica Biosystems are Danaher Companies
2. Overview • History of Immuno-Oncology • Types of Immunotherapy • Immunomodulatory agents • Personalized Cancer Vaccines • CAR-T cell therapy • Immune Checkpoint Inhibitors • Focus: Immune Checkpoint Biomarkers
3. Evolution of Cancer Immunotherapy • William Coley – 1890s surgeon • Coley’s toxin… • BCG, IFN-alpha, IL-2 • IL-2 applications in melanoma and RCC proved that advanced metastatic cancers can be controlled in some patients by stimulating T cells with cytokines • Critical development • CTLA-4 shown to be inhibitory for T cell responses by James Allison and Jeff Blu...
Biomarkers
AE1/AE3 (1)
AMACR (2)
BCL6 (1)
CD163 (2)
CD20 (2)
CD3 (9)
CD4 (5)
CD68 (5)
CD8 (10)
CDX2 (2)
CK20 (5)
Ck5 (4)
...
DESCRIPTION: Chromogenic multiplex IHC kit for BOND RX - human CD68, CD163, PD-L1
SIZE: 10 slides
PRODUCT OVERVIEW: Kit for chromogenic multiplex IHC staining of 10 slides plus a single negative control slide on the BOND RX with V7.0 software.
1° Antibody
Clone
1° Tag
2° Antibody
Chromogen
CD8
C68/684
UT021
Anti-UT021-AP
Leica Refine Red
CD163
EPR19518
UT015
Anti-UT015-HRP
Yellow
PD-L1
73-10
UT014
Anti-UT014-HRP
Leica Blue
Leica Refin...
Different types of cancers frequently metastase to bone tissue. Treatment planning decisions are often based upon histology and special staining of these distant sites of disease. These decisions may rely on the outcome of immunohistochemistry, in situ...
In recent years, digital pathology has gone from an intriguing idea to an integral part of how academic and commercial labs operate. Join Leica Biosystems and Procia Digital Pathology as they discuss why institutions are going digital today and how they...