HistoCore BIOCUT R - Mechanical Manual Rotary Microtome
149BIOR00C1, 14052158201
New Worlds Discovered - Research Reimagined
Faster Trimming and Consistent Cuts for all your Research Needs
HistoCore BIOCUT R facilitates faster trimming thanks to the new coarse feed wheel that lets you customize the direction of rotation. Built on 145+ years of market-leading microtomes, Leica Biosystems offers the next generation of microtomes with specially designed models for serial cutting with the actively cooled RM CoolClamp, which keeps the block cold longer for consistent slice thickness over multiple sections.
- Advance or retract the specimen according to your preference by manually turning the Personalized Coarse Feed Wheel.
- The new model allows you to switch between high and low-profile blades even faster without changing blade holders by using the 2-in-1 Blade Holder.
- Silent retraction produces little to no noise, allowing the user to work in a quiet environment, creating a comfortable user experience.
Specs
Product Specifications
General
Type: | Mechanical |
Nominal Supply Voltage: | N/A |
Nominal Frequency: | N/A |
Maximum Power Consumption: | N/A |
Protection Class: | N/A |
Power Fuses: | N/A |
Pollution Degree: | N/A |
Overvoltage Category: | N/A |
Maximum Heat Emission: | N/A |
Operating Temperature Range: | +18°C to +30°C |
Temperature Range During Storage: | +5°C to +50°C |
Relative Humidity During Operation: | 20% to Max. 80% Non-Condensing |
Relative Humidity During Storage: | 10% to Max. 85% Non-Condensing |
Dimensions & Weight
BASIC INSTRUMENT | |
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Width (including handwheel and coarse feed wheel): | 477 mm |
Depth (including waste tray): | 620 mm |
Height (without top tray): | 295 mm |
Weight (without accessories): | Approx. 31 kg |
CONTROL PANEL | |
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Type: | N/A |
Width: | N/A |
Depth: | N/A |
Height: | N/A |
Height (in inclined position): | N/A |
Weight (net): | N/A |
Microtome Performance Specs
Specimen Feed: | approx. 24 mm ±2 mm |
Vertical Stroke: | 70 mm ±1 mm |
Large Standard Clamp: 55 x 50 x 30 mm Super Cassette Clamp: 68 x 48 x 15 mm | |
Motorized Sectioning Speeds: | N/A |
SPECIMEN RETRACTION | |
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In Manual Sectioning Mode: | Approx. 40 µm (can be turned off) |
In Motorized Sectioning Mode: | N/A |
SPECIMEN ORIENTATION | |
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Horizontal: | ± 8° |
Vertical: | ± 8° |
SECTION THICKNESS SETTINGS | |
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Range: | 1 - 60 µm |
Setting Values: | 1 - 10 µm (in 1 µm increments) |
10 - 20 µm (in 2 µm increments) | |
20 - 60 µm (in 5 µm increments) |
TRIMMING SECTION THICKNESS SETTINGS: | |
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Range: | 10 µm, 30 µm |
Setting Values: | N/A |
Additional Specifications
Handwheel Balance System: | |
Handwheel Lock / Brake: | 2 Mechanical Locks |
Safety Hand Wheel: | N/A |
Coarse Feed Wheel Turn Direction: | User-Selectable - Clockwise or Counter-Clockwise |
WASTE TRAY | |
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Type | Standard |
Waste Tray Volume | 1400 ml |
SELECTABLE CUTTING MODES | |
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Rock Mode: | - manual |
Single Mode: | |
Continuous Mode: | |
Step Mode: | |
Program Mode: |
BLADE HOLDER | |
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Type: | 2-in 1 for high and low profile blades |
North-South Movement: | ± 24 mm |
East-West Movement: | N/A |
Lateral Displacement Function: | via knife holder CE clamping top |
SPECIAL FEATURES | |
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Remaining Feed Indicator | Visual |
Section Counter | |
Section Thickness Totalizer | |
Memory Position | |
Special Spindle for Precise Semi-Thin Sectioning | |
Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning | |
Precise 3D Object Head Stop Position |
Features
Product Features
Customized Settings for Comfort and Efficiency
Using the new adjustable manual coarse feed wheel, comfortably advance or retract the specimen.


Save Room on your Workbench - Store Tools on Top of your Microtome
Our new models feature 40% more surface area on top of the microtome. You can store even more of your necessary tools - brush, blades, wipes, and more.
Prepare High Quality Non-Human Paraffin Sections for all of your Research Needs
The microtome is specially designed for serial cutting with the actively cooled RM CoolClamp and the low-temperature block for consistent slice thickness over multiple sections. Switch between high and low-profile blades even faster without changing blade holders by using the 2-in-1 Blade Holder.


Precision Orientation System
Always get back to the 0-position on the microtome. The precision orientation system allows you to precisely position your specimen prior to sectioning.
Force Balance System
The unique force balance system handles various block sizes as well as the RM CoolClamp, which minimizes the risk of injury from an unbalanced object head.
Compare
Quick Compare Chart
Product |
![]() HistoCore BIOCUT R Currently viewing |
![]() HistoCore MULTICUT R |
![]() HistoCore AUTOCUT R |
![]() HistoCore NANOCUT R |
Type | Mechanical | Semi-Motorized | Motorized | Motorized |
Precision-Orientation System | ||||
Force Balance System | ||||
2-in-1 Blade Holder | ||||
Specimen Cooling Option with RM CoolClamp | ||||
Standard Waste Tray | ||||
Silent Retraction | ||||
Personalized Coarse Feed Wheel | ||||
Fast Homing | ||||
Memory Position | ||||
Electronic Brake | ||||
Special Spindle for Precise Semi-Thin Sectioning | ||||
Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning | ||||
Precise 3D Object Head Stop Position |
Documents
Documents
Brochure
Certificates
EU Declaration HistoCore BIOCUT R B en | (PDF) |
IFUs
Resources
Resources
Frequently Asked Questions
HistoCore Microtomes
Does the new HistoCore RM antistatic tray fit on the older RM22xx series?
No – the microtome base plates of both series have different dimensions and are not compatible with each other.
How does the new antistatic waste tray reduce contamination?
The antistatic waste tray is made from resistant antistatic material to avoid debris sticking to the walls of the tray.
Is the new 2-in-1 blade holder compatible as a whole assembly with the older RM22xx series?
Yes – only in the combination blade holder and 2-in-1 blade holder.
Can we still use the backlighting with the new blade holder base for the 2-in-1 blade holder?
No – the 2-in-1 blade holder base does not have the cut-out for the backlighting.
Which accessories of the older RM22xx Series cannot be used with the HistoCore RMs anymore?
- Small section waste tray
- Large section waste tray
- Top tray – HistoCore RM top tray is 40% larger than the RM22xx series tray
- Cooling Device – too small to be placed on instrument top. However, it’s still good to place next to the instrument
What is the advantage of the personalized coarse feed wheel?
Convenience and ease-of-user – users can select their personal preference of coarse feed wheel turn direction. This feature is preserved from the RM22xx series, allowing users to trim at the high pace.
What is the advantage of “Fast homing”?
The return speed of the object head from front to home position has been reduced from 26 seconds (older series) to 13 seconds (new series). This accelerated speed helps to shorten the sectioning process each time the object head is returned to home position.
What is the advantage of the Memory Position?
When batch trimming and using the same height of blocks, Memory Position will help to accelerate the sectioning.
- First insert a new block
- Bring the block to the blade
- Set the Memo position (stored)
- Trim
- Remove block for re-cooling
- Press “Memo” – the object head returns to the set object change position
- Insert a new block – check position
- Trim again
Configurations
Configurations
Choose your option below, and then use the Contact Us link above to submit a quote request for your selection
Configuration 1 (149BIOR00C1)
- Manual mechanical rotary microtome
- Includes Standard Section Waste Tray
- Top Tray
- Precision orientation with quick clamping system for specimen clamps
- Universal cassette clamp
- Two-in-one blade holder E for high and low-profile blades with lateral displacement function (includes blade holder base)
Basic Instrument (14052158201)
- Manual mechanical rotary microtome
- Includes Standard Section Waste Tray
- Top Tray
- Completely customizable with a wide selection of accessories