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- Histology Solutions
  - Histology Solutions
    - - Tracking and Workflow
      - Histology Consumables
    - Histology Solutions
      
      Fewer resources, more to do, and less time to get work done. While we can’t eliminate these pressures, we can help you make the most of each minute, meet your metrics, and consistently deliver slides on-time.
  - Histology Consumables
    - - Consumables
      - Ancillaries
      - VIEW ALL
    - Histology Consumables
      
      Improve quality, reduce errors, and save time with dedicated plug and play consumables. From glass slides and coverslips to wax and bulk reagents, smooth running of any laboratory depends on a consistent supply of high-quality consumables.
  - Tissue Processors
    - - HistoCore PELORIS 3 - High Throughput, 1hr Rapid Parallel Processing
      - HistoCore PEGASUS Plus - Medium Throughput, Parallel Processing + Tracking
    - Tissue Processors
      
      We know one size does not fit all. Our broad range of tissue processors means you can choose the right instrument for your laboratory's space, throughput, and workflow needs.
  - Embedding Centers
    - - HistoCore Arcadia - Embedding Center
      - HistoCore Arcadia C - Cold Plate
      - HistoCore Arcadia H - Embedding Station
      - View All
    - Tissue Embedding Centers
      
      Optimal tissue embedding is essential for smooth sectioning and ribboning.  Intelligent automation for precise temperature control coupled with flexible, ergonomic configuration enable efficient workflow and maximized productivity.
  - Microtomes
    - - HistoCore AUTOCUT - Automated Rotary Microtome
      - HistoCore MULTICUT - Semi-Automated Rotary Microtome
    - Clinical Microtomes
      
      The choice of Clinical or Research Microtomes from Leica Biosystems gives the precision, control, and comfort needed to get the best possible section from every block, every day.
  - Cryostats
    - Cryostats
      
      In surgery every moment matters. Intraoperative consultations require rapid responses to surgical staff. Safely deliver consistent, quality frozen sections - fast.
  - Slide Stainers & Coverslippers
    - - HistoCore SPECTRA Workstation
      - Leica CV5030 - Fully Automated Glass Coverslipper
      - Leica ST5010 Autostainer XL
      - View All
    - Slide Stainers & Coverslippers
      
      Life-changing diagnoses for every patient reside in every slide. Consistently deliver the high-quality staining your department demands with integrated stains, stainers and expert advice.
  - View All
- IHC & ISH
  - IHC & ISH
    - - BOND IHC-ISH Instruments & Solutions
      - IHC Primary Antibodies
    - IHC & ISH
      
      Whether delivering clinical diagnostics or the next research breakthrough, every moment matters. There is constant pressure to quickly produce reliable results. Meet the challenge with solutions engineered to address today’s needs and tomorrow’s opportunities.
  - BOND IHC-ISH Instruments & Solutions
    - BOND IHC-ISH Instruments & Solutions
      
      Every BOND system is complete, automated, and engineered for speed, reliability, and accuracy, with each configuration tailored to address specific diagnostic or discovery challenges.
  - IHC Primary Antibodies
    - IHC Primary Antibodies
      
      Create high-quality IHC slides with a complete solution of antibodies, ancillary reagents, and detection systems. Developed in-house with 20+ years of experience, these robust antibodies are optimized for automated and manual applications.
  - Molecular Solutions
    - - ThermoBrite - ISH/FISH Slide Denaturation/Hybridization Instrument
    - Molecular Solutions
      
      A comprehensive range of probes, detection, ancillaries, and instruments for automated or manual ISH detection in fluorescence and brightfield applications.
  - IHC & ISH Consumables
    - - Detection Systems
      - Companion Diagnostics
    - IHC & ISH Consumables
      
      Whether delivering clinical diagnostics or the next research breakthrough, every moment matters. There is constant pressure to quickly produce reliable results. Meet the challenge with solutions engineered to address today’s needs and tomorrow’s opportunities.
  - Companion Diagnostics
    - Learn More
    - Companion Diagnostics: Cutting Edge Collaboration
      
      Leica Biosystems global Companion Diagnostics team collaborates with biopharmaceutical companies to develop and commercialize solutions that could identify patients likely to benefit from our partners’ emerging therapies.
  - View All
- Digital Pathology
  - Digital Pathology
    - - Slide Scanners & Solutions
      - Management & Integration Software
    - Digital Pathology
      
      Adopting digital pathology is complex, but it doesn’t have to be complicated. Leica Biosystems can clarify your organization’s path to digitally driven discoveries or diagnostics. Our world-leading, modular technology is supported by experience with thousands of Aperio Digital Pathology implementations worldwide.
  - Slide Scanners & Solutions
    - - Aperio GT 450 DX - Automated, High Capacity Digital Pathology Slide Scanner
      - Aperio GT 450 - Automated, High Capacity Digital Pathology Slide Scanner
      - Aperio LV1 — Real-time Digital Pathology System
      - Aperio CS2 — High quality digital slides from your desktop
    - Scan - Aperio Digital Pathology Slide Scanners
      
      Scanning is the first step in digital pathology; put your best foot forward.  From translational research to routine diagnostics or AI development, there is an Aperio scanner for every need.
  - Management & Integration Software
    - - Aperio eSlide Manager with WebViewer DX
      - Aperio LIS Connectivity Solution – Integrated case data and whole slide images at your fingertips
    - Manage – Aperio Digital Pathology Software
      
      Effective image management and automated systems communication are essential for digital pathology success. Secure, scalable solutions with flexible deployment options enable anytime, anywhere access to your slides.
  - Aperio Clinical Solution
    - Aperio Clinical Solution - Proven Digital Pathology for Diagnostic Excellence
    - Aperio GT 450 DX - Automated, High Capacity Digital Pathology Slide Scanner
    - Aperio eSlide Manager with WebViewer DX
    - Aperio LIS Connectivity Solution – Integrated data and whole slide images at your fingertips
    - View All
    - Aperio Clinical Solution
      
      Aperio Clinical Solution elevates your diagnostic experience using the power of proven digital pathology –manifesting the potential of universal case access and borderless professional collaboration.
  - View All
- Research Solutions
  - Research Solutions
    - - BOND IHC-ISH Instruments & Solutions
      - Slide Scanners & Solutions
      - View All
    - Research Solutions
      
      Our purpose is to enable researchers to accelerate their journey, transforming scientific exploration into translational outcomes. Our goal is to shape the future with novel technologies that inspire every researcher’s exploration of biology.
  - Research Microtomes
    - - HistoCore NANOCUT R - Automated Research & Special Applications Rotary Microtome
      - View All
    - Research Rotary Microtomy Solutions
      
      Built on 145+ years of market-leading microtomes, Leica Biosystems offers the next generation of microtomes specially designed for research and industry.
  - Vibratomes
    - - Leica VT1000 S - Vibrating blade microtome
      - Leica VT1200 - Semi-Automatic Vibrating Blade Microtome
      - Leica VT1200 S - Fully automated vibrating blade microtome
      - View All
    - Vibratomes
      
      Vibrating microtomes (Vibratomes) by Leica Biosystems help you to accurately cut tissue under physiologial conditions without freezing or embedding.
  - Cryostats
    - Leica CM3600 XP - Whole Body Sectioning with GLP documentation
    - Learn More
    - Cryostats
      
      Cryostats for your Cancer or Neuroscience research needs.
  - BOND IHC-ISH Instruments & Solutions
    - - BOND RX - Fast Research Stainer
      - BOND RXᵐ - Compact Research Stainer
      - BOND RX-ADVANCE Advanced Research Staining Network
      - Learn More
    - BOND IHC-ISH Instruments & Solutions
      
      Every BOND system is complete, automated, and engineered for speed, reliability and accuracy with each configuration tailored to address discovery challenges.
  - Slide Scanners & Solutions
    - - Aperio GT 450 - Automated, High Capacity Digital Pathology Slide Scanner
      - Aperio CS2 — High quality digital slides from your desktop
      - Aperio LV1 — Real-time Digital Pathology System
    - Scan - Aperio Digital Pathology Slide Scanners
      
      Scanning is the first step in Digital Pathology; put your best foot forward. From translational research to routine diagnostics or AI development.
  - View All
Life Sciences
- Life Sciences Solutions
  - Life Sciences Solutions
    - - Specimen Preparation
      - IHC, ISH and Emerging Tests
      - View All
    - Life Sciences Solutions
      
      Our purpose is to enable researchers to accelerate their journey, transforming scientific exploration into translational outcomes. Our goal is to shape the future with novel technologies that inspire every researcher’s exploration of biology.
  - Specimen Preparation
    - - Research Microtomes - Research Rotary Microtomy Solutions
      - Vibratomes - Vibrating Blade Microtomy Solutions
    - Specimen Preparation
      
      From staining workstations, to a full offering of consumables, we are committed to supporting accurate and trusted results for your important daily work.
  - IHC, ISH and Emerging Tests
    - - BOND RX - Fast Research Stainer
      - BOND RXᵐ - Compact Research Stainer
      - Molecular Solutions
      - VIEW ALL
    - IHC, ISH and Emerging Tests
      
      Researchers need clear results to discover new treatments. BOND research instruments provide the flexibility you need to explore new possibilities, accurate results to ensure nothing is missed, and rapid, cost-effective operation so you can perform more tests.
  - Digital Pathology
    - - Aperio ImageScope - Pathology Slide Viewing Software
      - VIEW ALL
    - Digital Pathology
      
      Our digital slide scanning products offer unprecedented image quality, speed and reliability for whole slide imaging; making Aperio ePathology scanners the optimal choice for research professionals.
  - Consumables
    - - Detection Systems
      - ISH Probes - Molecular Pathology
      - IHC Primary Antibodies
      - VIEW ALL
    - Consumables
      
      Improve quality, reduce errors, and save time with dedicated plug and play consumables. From glass slides and coverslips to wax and bulk reagents, smooth running of any laboratory depends on a consistent supply of high-quality consumables.
  - View All
- Educational Resources
  - Educational Resources
    - - Testimonials
      - View All
    - Educational Resources
      
      Leica Biosystems provides complete access to today's hottest topics in life sciences and in tissue-based translational research.
  - Articles
    - Articles
      
      Articles by thought leaders across the fields of Histology, Anatomic Pathology and cancer research.
  - Webinars
    - Histology Hacks for Cryosectioning
    - The Power of Spatially Resolved Staining
    - Modernization of Tissue-based, Biomarker-led Clinical Research
    - VIEW ALL
    - Webinars
      
      Live and recorded scientific educational resources presented by industry thought leaders.
  - White Papers and Case Studies
    - Strategies for Spatial Multi-omics: Co-detection of protein and RNA biomarkers on a single FFPE tissue section powered by InSituPlex® Technology
    - View All
    - White Papers and Case Studies
      
      Selected in-depth reviews of current practices and evidence-based solutions for the research community.
  - Peer-Reviewed Publications
    - VIEW ALL
    - Peer-Reviewed Publications
      
      The Leica Biosystems Life Science peer-reviewed publication repository offers a method for building a bibliography of scientific publications referencing Leica Biosystems Life Sciences products.
  - How to Guides
    - - Top Considerations When Buying a Digital Pathology Scanner
      - VIEW ALL
    - How to Guides
      
      Access additional educational resources to support your applications, including content with technical knowledge and "how-to" guides.
  - Image Gallery
    - - Digital Pathology Gallery
      - IHC Staining Image Gallery
    - Image Gallery
      
      Experience the interactive digital pathology image gallery with whole slide images scanned on the Aperio GT 450 slide scanner.
  - Testimonials
    - Learn More
    - Inspirational Research: Our Customers Share Their Stories
      
      Researchers share how they utilize spatial multi-omics techniques on the BOND RX fully automated staining platform.
- Applications
  - Applications
    - - Whole Slide Imaging
      - View All
    - Applications
      
      Leica Biosystems research portfolio provides instruments, solutions, and support for each step of your tissue-based journey; from biomarker to digital analysis, and beyond.
  - Pre-Analytics and Histology Research Solutions
    - Learn More
    - Pre-Analytics and Histology Research Solutions
      
      Quality, once lost, cannot be regained. Upstream pre-analytic quality is imperative to generating high-caliber data for exploring spatial biology, from IHC to multiplexing to plotting the tumor microenvironment.
  - Integrated Translational Research Solutions
    - LEARN MORE
    - Integrated Translational Research Solutions
      
      Translational research projects are as novel as the technologies that drive them. We support scientists with solutions that bring automation, flexibility, and optimization to scale up your success and move quickly and efficiently into practical application.
  - Multiplexing
    - LEARN MORE
    - Multiplexing
      
      Modern Multiplex Solutions for the Research Lab
      
      Multiplexing addresses the need for researchers to assess multiple biomarkers (protein and/or nucleic acid markers) at specific locations within a tissue sample
  - Whole Slide Imaging
    - Learn More
    - Whole Slide Imaging
      
      Whole Slide Imaging (WSI) is revolutionizing the field of pathology, ushering in an era of unprecedented access to Image quality, ease of use, and speed. WSI allows for the digital acquisition and storage of tissue slides and has immense practical implications for researchers.
  - View All
- Partnerships
  - Innovation Partnerships
    - - NanoString
      - Advanced Cell Diagnostics (ACD)
      - View All
    - Innovation Partnerships
      
      Our Open Innovation (OI) partnerships enable easy integration across technologies, supporting fluorescent and chromogenic protocols, and helping to answer your most pressing research questions.
- Events
  - Events
    - Learn More
    - Events
      
      Learn from industry professionals at our live and on-demand webinars, or join us in-person to meet industry experts, network with peers, and explore the translational research space with us. View our range of live events and complimentary webinars.
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Life Sciences and Research Solutions
Advanced Staining Image Gallery

Advanced Staining Image Gallery

Biomarkers

AE1/AE3 (1)

AMACR (2)

BCL6 (1)

CD163 (2)

CD20 (2)

CD3 (9)

CD4 (5)

CD68 (5)

CD8 (10)

CDX2 (2)

CK20 (5)

Ck5 (4)

Colocalization (1)

Counterstain (17)

Desmin (5)

FoxP3 (2)

Ki67 (5)

Napsin A (3)

P63 (1)

PD-1 (2)

PD-L1 (5)

PDL1 (3)

Pan-CK (6)

Serotonin (4)

TTF-1 (3)

p40 (3)

Tissue

Bladder (3)

Colon (7)

Lung (5)

Lymph Node (2)

Prostate (2)

Rectum (1)

Tonsil (6)

Plex Type

3-Plex (3)

4-Plex (6)

Chromo Multiplex IHC - 2-Plex (5)

Chromo Multiplex IHC - 3-Plex (5)

Chromo Multiplex IHC - 4-Plex (3)

Chromo Multiplex IHC - 5-Plex (4)

Lung - Adenocarcinoma

Tissue:

Lung

Biomarkers:

TTF-1, Napsin A, Counterstain

Color:

TTF-1 - Red, Napsin A - Green, Counterstain - Red

Plex Types:

Chromo Multiplex IHC - 2-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Lung - Squamous cell Carcinoma

Tissue:

Lung

Biomarkers:

P63, Napsin A, TTF-1, Counterstain

Color:

P63 - Red, Napsin A - Blue, TTF-1 - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 3-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Tonsil - Normal

Tissue:

Tonsil

Biomarkers:

PDL1, CD68, CD8, Pan-CK, Counterstain

Color:

PDL1 -Red, CD68 - Brown (DAB), CD8 - Blue, Pan-CK - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 4-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Colon - Normal

Tissue:

Colon

Biomarkers:

Serotonin, Ki67, CD3, CK20, Desmin, Counterstain

Color:

Serotonin - Red, Ki67 - DAB (Brown), CD3 - Blue, CK20 - Purple, Desmin - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 5-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Tonsil - Normal

Tissue:

Tonsil

Biomarkers:

BCL6, Ki67, Counterstain, Colocalization

Color:

BCL6 - Red, Ki67 - Green, Counterstain - Hematoxylin, Colocalization - Purple

Plex Types:

Chromo Multiplex IHC - 2-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Prostate - Adenocarcinoma

Tissue:

Prostate

Biomarkers:

AMACR, p40, Ck5, Counterstain

Color:

AMACR - Red, p40 - DAB (Brown), Ck5 - Blue, Counterstain - Red

Plex Types:

Chromo Multiplex IHC - 3-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Tonsil - Normal

Tissue:

Tonsil

Biomarkers:

CD4, CD8, AE1/AE3, Counterstain

Color:

CD4 - Red, CD8 - DAB (Brown), AE1/AE3 - Green, Counterstain - Red

Plex Types:

Chromo Multiplex IHC - 3-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Colon - Adenocarcenoma

Tissue:

Colon

Biomarkers:

CDX2, CD3, Counterstain

Color:

CDX2 - Red, CD3 - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 2-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Colon - Carcinoma

Tissue:

Colon

Biomarkers:

Serotonin, Ki67, CD3, CK20, Desmin, Counterstain

Color:

Serotonin - Red, Ki67 - DAB (Brown), CD3 - Blue, CK20 - Purple, Desmin - Green, Counterstain - Red

Plex Types:

Chromo Multiplex IHC - 5-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Colon - Carcinoma

Tissue:

Colon

Biomarkers:

Serotonin, Ki67, CD3, CK20, Desmin, Counterstain

Color:

Serotonin - Red, Ki67 - DAB (Brown), CD3 - Blue, CK20 - Purple, Desmin - Green, Counterstain - Red

Plex Types:

Chromo Multiplex IHC - 5-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Colon - Normal

Tissue:

Colon

Biomarkers:

CK20, Desmin, CD3, CDX2, Counterstain

Color:

CK20 - Red, Desmin - DAB (Brown), CD3 - Blue, CDX2 - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 4-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Tonsil - Normal

Tissue:

Tonsil

Biomarkers:

PDL1, PDL1, CD8, Pan-CK, Counterstain

Color:

PDL1 -Red, CD68 - Brown (DAB), CD8 - Blue, Pan-CK - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 4-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Lung - Adenocarcinoma

Tissue:

Lung

Biomarkers:

Ck5, TTF-1, Napsin A, Counterstain

Color:

CK5 - DAB (Brown), TTF-1 - Red, Napsin A - Blue, Counterstain - Red

Plex Types:

Chromo Multiplex IHC - 3-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Colon - Normal

Tissue:

Colon

Biomarkers:

Serotonin, Ki67, CD3, CK20, Desmin, Counterstain

Color:

Serotonin - Red, Ki67 - DAB (Brown), CD3 - Blue, CK20 - Purple, Desmin - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 5-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Prostate - Adenocarcinoma

Tissue:

Prostate

Biomarkers:

AMACR, p40, Ck5, Counterstain

Color:

AMACR - Red, p40 - DAB (Brown), Ck5 - Blue, Counterstain - Red

Plex Types:

Chromo Multiplex IHC - 3-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Lung - Squamous cell Carcinoma

Tissue:

Lung

Biomarkers:

p40, Ck5, Counterstain

Color:

p40 - Red, CK5 - Green, Counterstain - Hematoxylin

Plex Types:

Chromo Multiplex IHC - 2-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

Tonsil - Normal

Tissue:

Tonsil

Biomarkers:

CD3, Counterstain, CD20

Color:

CD3 - Green, Counterstain - Hematoxylin, CD20 - Red

Plex Types:

Chromo Multiplex IHC - 2-Plex

Related Products:

BOND RX Fully Automated Research Stainer

Related Topics:

Chromogenic multiplexing, Digital Pathology, Automated IHC, Cancer Research

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Service Emails:

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