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IHC & Multiplexing

Researchers need clear results to discover new treatments. BOND RX fully automated research stainers provide the flexibility you need to explore new possibilities, accurate results to ensure nothing is missed, and rapid, cost-effective operation so you can perform more tests.

Modern Multiplex Solutions for the Research Lab

Multiplexing addresses the need for researchers to assess multiple biomarkers (protein and/or nucleic acid markers) at specific locations within a tissue sample. The information revealed through simultaneous detection of multiple markers, the spatial relationships among cells and tissue in disease, and the heterogeneity are now understood to be critical to developing effective therapeutic strategies.

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Automated Multiplex Immunofluorescence

Bethany Remeniuk PhD, Global Applications Scientist, Akoya Biosciences, Inc.
Traci DeGeer BS, HT (ASCP) HTL, QIHC, Director, Advanced Staining Innovation, Leica Biosystems

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What Are Life Sciences?

Shubham Dayal Senior Medical Writer, Medical and Scientific Affairs at Leica Biosystems
Jack Heath Medical Science Liaison, PhD

This article is the first of a 4-part series including the following topics: “What is life science” (current feature), “Translational Research,” “Spatial Research,” and “Biomarkers in Translational/Spatial Research.

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Multiplexing In Tissue-Based Research: Chromogenic Staining and Automation

Rhian Evans Ph.D., Scientist

Immunohistochemistry (IHC) detects proteins of interest within whole tissue sections, keeping cellular organization intact.

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Tips, Tricks, and Optimization: A User's Guide to BOND RX and Chromogenic Multiplexing in Research Applications

Mark Lawson, Applications Specialist, Leica Biosystems

In this webinar, Mark Lawson, Life Science Field Applications Specialist at Leica Biosystems, shares the development timeline of IHC and multiplex staining on the BOND RX staining instrument, and its role in driving cutting-edge technologies.

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Multiplex Fluorescence Immunohistochemistry using the Ultivue InSituPlex Platform on the Leica Biosystems BOND RX

Traci DeGeer BS, HT (ASCP) HTL, QIHC, Director, Advanced Staining Innovation, Leica Biosystems
Alexander Klimowicz Senior Principal Scientist, Boehringer Ingelheim Pharmaceuticals

Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the analysis of target protein expression in subsets of specific cells within the context of histopathological features of disease.

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The BOND RX Stainer - Automated Multiplexing Solutions

Rhian Evans Ph.D., Scientist

Leica Biosystems BOND RX stainer can aid biomarker and drug discovery by offering fast, customized, consistent, fluorescent or chromogenic multiplex IHC and ISH on your research samples. The result? Freeing up your time to innovate, investigate and discover!

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Modernization of Tissue-based, Biomarker-led Clinical Research

Dr Stephanie G. Craig, Lecturer in Precision Medicine at the Patrick G. Johnson Centre for Cancer Research, Queen's University Belfast

In this webinar, learn how the Centre for Cancer Research at the Queen’s University Belfast utilized automated staining and slide digitization as an aid to clinical research (for research use only. Not for use in diagnostic procedures) in immunohistochemistry, RNA in situ hybridization, multiplex immunofluorescence, and artificial intelligence studies.

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Validating Antibodies for Research Applications in IHC

Will Howat PhD, Director of Antibody Validation & Characterisation, Abcam
Damian Cockfield Global Product Manager - BOND, Leica Biosystems

The importance of building a validation structure within your lab cannot be overstated. Once in place, the ability to identify high-quality specific results compared to spurious, non-specific antibody staining on tissue will be easier and allow the researcher to focus on downstream applications, such as single and multiplex IHC.

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For Research Use Only. Not for use in Diagnostic Procedures.