Leica CM3050 S Cryostat
Processing multiple specimen and performing serial cuts can result in high section numbers. Nevertheless, reproducibility can't be compromised. Permanent attention to detail and many hours in front of the cryostat can be exhausting for the user. The Leica CM3050 S cryostat is designed to help with exactly these time-consuming jobs.
The low working height and available knee space of the Leica CM3050 S cryostat allow the user to work comfortably while sitting. Motorized drive and section counter improve productivity for multiple serial sections.
Particularly when working with delicate specimens, e.g. brain samples, the precise specimen orientation and the specimen feed system provide for reproducible sections.
Specs
Technical Specifications
General
Width: | 882 mm |
Depth: | 766 mm |
Height: | 1040 mm |
Weight (incl. microtome): | approx. 180 kg |
Temperature setting range: | 0°C to -40°C |
Maximum specimen size: | 40 x 55 mm |
Cutting speed: | 0.1 mm/s to 170 mm/s 0.1 mm/s to 100 mm/s Vmax: 210 mm/s |
Section thickness setting | 0.5 to 300 μm |
Maximum specimen size | 40 mm x 55 mm |
Horizontal specimen feed | 25 mm |
Vertical specimen stroke | 59 mm |
Specimen retraction | 50 pm |
Specimen precision orientation | by 8° (x/y/z axis) |
Trimming | 5 to 150 μm ± 0,5 μm in steps of 5, 10, 30, 50, 100 and 150 μm |
Motorized coarse feed at two speeds | 500 μm/s and 1,000 μm/s |
Cutting speed ranges | 0.1 mm/s to 170 mm/s, 0.1 mm/s to 100 mm/s, Vmax 210 mm/s |
Temperature setting range | 0°C to -40°C |
Defrosting | programmable 1 automatic defrost cycle/24 h duration; from 6 to 12 min; manual defrosting |
Freezing shelf temperature | Approx. -43°C at an ambient temperature of 22°C |
Temperature setting range | -10°C to -50°C (+/-3 K) |
Dimensions (W x H x D) | 882 x 1040 x 766 mm |
Weight (including microtome) | Approx. 180 kg |
Power draw | 1800 VA |
Features
Product Features
Precision Sectioning
When working with large samples, accurate specimen orientation and feed are crucial. The precise specimen orientation system with zero position provides for x/y adjustment of up to 8°. The specimen feed system with 25mm horizontal feed allows for reproducible thin sections.


Precision Cooling
An independent refrigeration system for the object head provides for temperature changes and efficient specimen temperature control to adjust for difficult samples such as brain or fatty tissue.
Highly efficient insulating materials and a dedicated cooling system support stable cryochamber temperatures, even when producing serial sections all day long.
Stay Organized
With critical items at hand, you can focus on your sectioning job. Freezing stage and tool tray in a large cryochamber, as well as an easily accessible storage area on top of the cryostat help you staying organized. The motor drive with foot-pedal enables you to have both hands free for sample handling.


Stay Focused
Section thickness totalizer and counter with reset button facilitate target preparation and promote fast trimming between levels. With the reverse section counter, a preselected number of sections can be carried out in both sectioning and trimming mode.
Comfortable Sitting Position
The Leica CM3050 S cryostat with its low working height and available knee space allows the user to work comfortably while sitting.
The optional electrohydraulic height adjustment grants tall users an adjustable working height and even more knee space. For users who prefer standing when sectioning, the height adjustment can lift the instrument up to standing working height.

Documents
Documents
Brochures
95.8846 CM3050 S Brochure EN | (PDF) |
95.8847 CM3050 S Brochure DE | (PDF) |
95.8848 CM3050 S Brochure FR | (PDF) |
95.8849 CM3050 S Brochure ES | (PDF) |
95.8850 CM3050 S Brochure IT | (PDF) |
Certificates
EU Declaration Leica CM3050s A en | (PDF) |
Material Safety Data Sheets
User Manuals/IFUs
Configurations
Configurations
Choose your option below, and then use the Contact Us link above to submit a quote request for your selection
Configuration 1 (14903050S01)
- Freestanding, motorized open-top cryostat with independent specimen temperature control.
- Spacious, easy-to-clean cryochamber with illumination.
- Removable heated glass sliding window.
- Cryochamber temperature setting down to -40 °C in 1° steps.
- Permanently cooled (down to -45 °C) quick-freeze shelf for 10 specimen discs.
Configuration 2 (14903050S02)
- Leica CM3050 S Configuration 120 V / 60 Hz With sectioning motor and with specimen temperature control with knife holder CN
- Freestanding, motorized open-top cryostat with independent specimen temperature control.
- Spacious, easy-to-clean cryochamber with illumination.
- Removable heated glass sliding window.
- Cryochamber temperature setting down to -40 °C in 1°increments.
- Permanently cooled (down to -45 °C) quick-freezeshelf for 10 specimen discs.
Basic Instrument (14903050S03)
- Leica CM3050 S Configuration 120 V / 60 Hz with sectioning motor, without specimen temperature control
- Freestanding, motorized open-top cryostat without independent specimen temperature control.
- Spacious, easy-to-clean cryochamber with illumination.
- Removable heated glass sliding window.
- Cryochamber temperature setting down to -40 °C in 1° steps.