8 result(s) for 'CK20'
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Antigen Background
Cytokeratin 20 has been demonstrated to be almost entirely confined to the gastric and intestinal epithelium, urothelium and Merkel cells of the skin. Cytokeratin 20 is less acidic than other type I cytokeratins and is of interest due to its restricted tissue expression. In normal tissue, cytokeratin 20 is expressed in intestinal epithelium, gastric foveolar epithelium, a number of endocrine cells in the upper portions of the p...
With the advent of the molecular techniques in the past ten years, there has been a steady increase in the utility of the diagnostic and predictive biomarkers in human tumors. In this educational exercise we will first examine what is the nature of these...
Biomarkers
AE1/AE3
AMACR
BCL6
CD20
CD3
CD4
CD68
CD8
CDX2
CK20
Ck5
Colocalization
Counterstain
...
Immunohistochemistry (IHC) is used in histology to detect the presence of specific protein markers that can assist with accurate tumor classification and diagnosis. This article provides an overview and the basic steps used to create an optimal IHC stain.