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Aperio GT 450 DX - Automated, High Capacity Digital Pathology Slide Scanner

Aperio GT 450 DX - Automated, High Capacity Digital Pathology Slide Scanner
IT Professional Login Screen
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Priority Slides
The Aperio GT 450 is fully compatible with the racks from the HistoCore SPECTRA Staining & Coverslipping Workstation
Pathologist Monitors
Aperio GT 450 DX - Automated, High Capacity Digital Pathology Slide Scanner
IT Professional Login Screen
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Priority Slides
The Aperio GT 450 is fully compatible with the racks from the HistoCore SPECTRA Staining & Coverslipping Workstation
Pathologist Monitors

Overview

Fast-Forward to Next Generation Imaging

The Aperio GT 450 DX is designed to scale up digital pathology operations by increasing throughput in high volume clinical pathology laboratories. The system uses innovative color calibration technology to output consistent high-quality images enabling on-time, on-screen diagnosis. Aperio GT 450 DX is an automated, high capacity digital pathology slide scanner that offers exceptional image quality, rapid delivery of cases and high-performance streamlined digital viewing built with the pathologist in mind.

  • Improve case turnaround with no touch scanning and continuous loading of the racks directly from the HistoCore SPECTRA Workstation (Stainer & Coverslipper)
  • Increase IT security and control with a dedicated Scanner Administrator Manager DX (SAM) server and software that allows you to set up and monitor multiple Aperio GT 450 DX scanners at a time. No more single workstations for each scanner
  • Ensure excellent image quality with Leica optics
Contact Us to get a quote. Call 00 308 321 0320 to speak with a representative.

For In Vitro Diagnostic Use.

Aperio GT 450 DX DOWNLOAD THE BROCHURE NOW!

Fast and Easy to Operate for Histotechnicians

The Aperio GT 450 DX is simple to operate and helps histotechnicians deliver rapid results with confidence. Complete scanning quickly and easily so you can focus on other tasks in the lab: 15 racks of 30 slides (450 slides total) can be loaded directly from HistoCore SPECTRA CV Coverslipper into the GT 450 DX. The slides are then automatically scanned at 81 slides per hour at 40x for a 15mm x 15mm area.

  • No touch continuous loading during scanning
  • Automated IQ checks during each scan to ensure quality
  • Assign priority cases
  • Every slide is calibrated with each scan
  • 450-slide capacity packed into a small size fits on the lab bench
  • 99.5% accurate tissue finder that allows you to adjust if needed*
  • 100% first-time barcode scan success rate*

*VP-0463 validation results

From the lab to the IT room to the office, the Aperio GT 450 DX was designed to scale up digital pathology operations for histotechnicians, IT professionals and pathologists.

Fast and Easy to Operate
Aperio GT 450 DX can be loaded directly from HistoCore SEPCTRA CV Coverslipper

Secure, Scalable Architecture for IT Professionals

The Aperio GT 450 DX offers fast, secure, and flexible IT architecture. A centralised SAM server and dedicated software provides you with a data management solution that can remotely set up and monitor multiple Aperio GT 450 DX scanners at a time.*

  • Comprehensive cybersecurity including encryption and login controls
  • centralised scanner management to set up and monitor multiple scanners
  • Two 10GB network connections on the SAM server
  • Scalable set up for hub and spoke configurations
  • Supports dedicated logins for each Aperio GT 450 DX scanner

*See Resources > FAQ for more info on SAM

Secure, Scalable IT Architecture

Excellent Image Quality for Pathologists

The Aperio GT 450 DX uses a high=performance objective manufactured by Leica Microsystems, renowned for producing world-class optics since 1849. This historic craftmanship is now built into the today’s Aperio GT 450 DX, which is designed to rapidly deliver images with exceptional quality for Pathologists.

  • Leica optics deliver exceptional image quality
  • Every slide is calibrated during scanning to ensure the best quality image
  • Automated image quality assessment, so you don’t have to send slides back for re-scans
  • 99.5% accurate tissue finder finds faint tissue while excluding pen marks, dust, and residue
Excellent Image Quality with Custom-Made Leica Objective
Custom-made Leica objective for next generation scanning,
csm_GT_450_Image_for_website_a20f3ca405

Image Quality Tested by Pathologists for Pathologists

(for diagnostic review, use Aperio DX Viewer on the Aperio DX Viewing Station, which includes a calibrated monitor)

Mitotic Events (Breast)
Mitotic Events (Breast)
Intercellular Bridges
Intercellular Bridges
Chromatin
Chromatin
Nucleoli
Nucleoli

Precision, Potential to Scale, and Peace of Mind

Digital pathology scan speeds have not always been fast enough at 40x magnification to keep up with high-volume scanning (120k+ slides per year). Real-Time Focusing (RTF)** offers a potential solution to this problem. It’s a novel method to capture a digital image that combines an imaging line sensor and a focusing line sensor.

  1. While scanning, the focusing line sensor receives focusing data of the tissue.
  2. Proprietary algorithms determine the best focus value.
  3. Then, each best focus value is treated like a control loop with the mechanics, feeding the best focus value to the objective height on the fly.
  4. The positioning adjustments of the objective are performed continuously (in real time) in order to enable the imaging line sensor to capture the image at its best possible focus. Hence, real time focusing.

**US Patent no. 9,841,590

Cellular Groves (Thyroid)
Cellular Groves (Thyroid)

Excellent Image Quality with Custom-Made Leica Objective

The high-performance objectives included with the Aperio GT 450 DX is specifically designed to maximise field of view for high speed digital pathology scanning. Most objectives are designed similarly to the human eye: round, which focuses light in the center and limits field of view. The objectives on the Aperio GT 450 DX includes an extra-wide flat field correction that enables a much larger field of view (1mm) that can accommodate extremely large digital images for fast scans and 0.26 um/pixel resolution at 40x magnification.

Excellent Image Quality with Custom-Made Leica Objective

Specifications

Imaging, Capacity & Operations
Dimensions & Weight
IT Requirements & Integration
Security Features
Slides, Coverslips & Labels

Downloads

View all available downloads below
Case Study - GT 450 DX - VISION24 -Assessing Image Quality A Comparative Multi-Assessment Evaluation - EN (200566 Rev. A) Case Study - GT 450 DX - VISION24 - Assessing Timing and Efficiency A Comparative Evaluation - EN (200658 Rev. A) Whitepaper - Real Time Focusing DX - EN (200394 Rev. A) White Paper - Your Focus is Our Objective - EN (200395 Rev. A) Case Study - Hanna et al 05 DEC 2024 240744 Rev A Case Study - Bauer et al precision 05 DEC 2024 240782 Rev A White Paper - DICOM 3 DEC 2024 240796 Rev B
Aperio GT 450 DX User Guide English MAN-0475 Rev C Aperio GT 450 DX Specifications English MAN-0479 Rev E Aperio GT 450 DX Quick Reference Guide English MAN-0477 Rev C Aperio GT 450 DX IT Manager and Lab Administrator Guide English MAN-0483 Rev C Aperio GT 450 DX Documentation Map English MAN-0498 Rev A
Aperio GT 450 DX Specifications Czech MAN-0479-cs Rev A Aperio GT 450 DX User Guide Czech MAN-0475-cs Rev B Aperio GT 450 DX Quick Reference Guide Czech MAN-0477-cs Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Czech MAN-0483-cs Rev B Aperio GT 450 DX Documentation Map Czech MAN-0498-cs Rev A
Aperio GT 450 DX User Guide Danish MAN-0475-da Rev B Aperio GT 450 DX Specifications Danish MAN-0479-da Rev A Aperio GT 450 DX Quick Reference Guide Danish MAN-0477-da Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Danish MAN-0483-da Rev B Aperio GT 450 DX Documentation Map Danish MAN-0498-da Rev A
Aperio GT 450 DX User Guide Dutch MAN-0475-nl Rev B Aperio GT 450 DX Specifications Dutch MAN-0479-nl Rev A Aperio GT 450 DX Quick Reference Guide Dutch MAN-0477-nl Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Dutch MAN-0483-nl Rev B Aperio GT 450 DX Documentation Map Dutch MAN-0498-nl Rev A
Aperio GT 450 DX User Guide Finnish MAN-0475-fi Rev B Aperio GT 450 DX Specifications Finnish MAN-0479-fi Rev A Aperio GT 450 DX Quick Reference Guide Finnish MAN-0477-fi Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Finnish MAN-0483-fi Rev B Aperio GT 450 DX Documentation Map Finnish MAN-0498-fi Rev A
Aperio GT 450 DX User Guide French MAN-0475-fr Rev C Aperio GT 450 DX Specifications French MAN-0479-fr Rev C-1 Aperio GT 450 DX Quick Reference Guide French MAN-0477-fr Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide French MAN-0483-fr Rev C Aperio GT 450 DX Documentation Map French MAN-0498-fr Rev A
Aperio GT 450 DX User Guide German MAN-0475-de Rev C Aperio GT 450 DX Specifications German MAN-0479-de Rev C-1 Aperio GT 450 DX Quick Reference Guide German MAN-0477-de Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide German MAN-0483-de Rev C Aperio GT 450 DX Documentation Map German MAN-0498-de Rev A
Aperio GT 450 DX User Guide Greek MAN-0475-el Rev B Aperio GT 450 DX Specifications Greek MAN-0479-el Rev A Aperio GT 450 DX Quick Reference Guide Greek MAN-0477-el Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Greek MAN-0483-el Rev B Aperio GT 450 DX Documentation Map Greek MAN-0498-el Rev A
Aperio GT 450 DX User Guide Italian MAN-0475-it Rev C Aperio GT 450 DX Specifications Italian MAN-0479-it Rev C Aperio GT 450 DX Quick Reference Guide Italian MAN-0477-it Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Italian MAN-0483-it Rev C Aperio GT 450 DX Documentation Map Italian MAN-0498-it Rev A
Aperio GT 450 DX User Guide Norwegian MAN-0475-no Rev B Aperio GT 450 DX Specifications Norwegian MAN-0479-no Rev A Aperio GT 450 DX Quick Reference Guide Norwegian MAN-0477-no Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Norwegian MAN-0483-no Rev B Aperio GT 450 DX Documentation Map Norwegian MAN-0498-no Rev A
Aperio GT 450 DX User Guide Polish MAN-0475-pl Rev B Aperio GT 450 DX Specifications Polish MAN-0479-pl Rev A Aperio GT 450 DX Quick Reference Guide Polish MAN-0477-pl Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Polish MAN-0483-pl Rev B Aperio GT 450 DX Documentation Map Polish MAN-0498-pl Rev A
Aperio GT 450 DX User Guide Portuguese-Portugal MAN-0475-pt-PT Rev B Aperio GT 450 DX Specifications Portuguese-Portugal MAN-0479-pt-PT Rev A Aperio GT 450 DX Quick Reference Guide Portuguese-Portugal MAN-0477-pt-PT Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Portuguese-Portugal MAN-0483-pt-PT Rev B Aperio GT 450 DX Documentation Map Portuguese-Portugal MAN-0498-pt-PT Rev A
Aperio GT 450 DX User Guide Russian MAN-0475-ru Rev B Aperio GT 450 DX Specifications Russian MAN-0479-ru Rev A Aperio GT 450 DX Quick Reference Guide Russian MAN-0477-ru Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Russian MAN-0483-ru Rev B Aperio GT 450 DX Documentation Map Russian MAN-0498-ru Rev A
Aperio GT 450 DX User Guide Serbian MAN-0475-sr Rev B Aperio GT 450 DX Specifications Serbian MAN-0479-sr Rev A Aperio GT 450 DX Quick Reference Guide Serbian MAN-0477-sr Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Serbian MAN-0483-sr Rev B Aperio GT 450 DX Documentation Map Serbian MAN-0498-sr Rev A
Aperio GT 450 DX User Guide Slovak MAN-0475-sk Rev B Aperio GT 450 DX Specifications Slovak MAN-0479-sk Rev A Aperio GT 450 DX Quick Reference Guide Slovakian MAN-0477-sk Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Slovak MAN-0483-sk Rev B Aperio GT 450 DX Documentation Map Slovak MAN-0498-sk Rev A
Aperio GT 450 DX User Guide Slovenian MAN-0475-sl Rev B Aperio GT 450 DX Specifications Slovenian MAN-0479-sl Rev A Aperio GT 450 DX Quick Reference Guide Slovenian MAN-0477-sl Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Slovenian MAN-0483-sl Rev B Aperio GT 450 DX Documentation Map Slovenian MAN-0498-sl Rev A
Aperio GT 450 DX User Guide Spanish-Latin-America MAN-0475-es-LA Rev B Aperio GT 450 DX Specifications Spanish-Latin-America MAN-0479-es-LA Rev A Aperio GT 450 DX Quick Reference Guide Spanish-LatinAmerica MAN-0477-es-LA Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Spanish-LatinAmerica MAN-0483-es-LA Rev B Aperio GT 450 DX Documentation Map Spanish-LatinAmerica MAN-0498-es-LA Rev A
Aperio GT 450 DX User Guide Spanish-Spain MAN-0475-es-ES Rev B Aperio GT 450 DX Specifications Spanish-Spain MAN-0479-es-ES Rev A Aperio GT 450 DX Quick Reference Guide Spanish-Spain MAN-0477-es-ES Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Spanish-Spain MAN-0483-es-ES Rev B Aperio GT 450 DX Documentation Map Spanish-Spain MAN-0498-es-ES Rev A
Aperio GT 450 DX User Guide Swedish MAN-0475-sv Rev B Aperio GT 450 DX Specifications Swedish MAN-0479-sv Rev A Aperio GT 450 DX Quick Reference Guide Swedish MAN-0477-sv Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Swedish MAN-0483-sv Rev B Aperio GT 450 DX Documentation Map Swedish MAN-0498-sv Rev A
Aperio GT 450 DX User Guide Turkish MAN-0475-tr Rev B Aperio GT 450 DX Specifications Turkish MAN-0479-tr Rev A Aperio GT 450 DX Quick Reference Guide Turkish MAN-0477-tr Rev A Aperio GT 450 DX IT Manager and Lab Administrator Guide Turkish MAN-0483-tr Rev B Aperio GT 450 DX Documentation Map Turkish MAN-0498-tr Rev A
Aperio GT 450 DX Release 1.2.5 Patch Notice PN-0080-Rev-A Aperio GT 450 DX 1.2.4 Patch Notice PN-0070-Rev-A Aperio GT 450 DX Release 1.2.2 Patch Notice PN-0064-Rev-A Aperio GT 450 DX 1.2 Patch Notice PN-0040-Rev-A Aperio GT 450 DX 1.1.3 Patch Notice - English PN-0038-Rev-A Aperio GT 450 DX 1.1.1 and 1.1.2 Patch Notice - English PN-0035-Rev-A Mirth Connect 4.4.2 Upgrade for Aperio SAM DX Server and Aperio GT 450 DX on Windows Server 20162019 Patch Notice PN-0051-Rev-A Aperio GT 450 SAM DX Software Versions 1.1 and 1.2 with Windows Server 2022 Patch Notice PN-0054-Rev-A

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