Science of H&E
Download this training resource to learn more about routine staining with hematoxylin and eosin (H&E) and the steps involved with the staining process.
Why Do We Stain?
In order to deliver a medical diagnosis, tissues must be examined under a microscope. Once a tissue specimen has been processed by a histology lab and transferred onto a glass slide, it needs to be appropriately stained for microscopic evaluation. This is because unstained tissue lacks contrast: when viewed under the microscope, everything appears in uniform dull grey color.
What Does "Staining" Do?
- Contrasts different cells
- Highlights particular features of interest
- Illustrates different cell structures
- Detects infiltrations or deposits in the tissue
- Detects pathogens
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