White Papers and Case Studies

Aperio GT 450 Improves Throughput by 64% and Reduces QC Tech Time by 94% in Workflow Study

Lance Mikus ,
MBA, Director of Product Management - Image Capture Systems at Leica Biosystems
Ashley Troutman ,
MBA, HT(ASCP), QIHC, CLSSBB.
Julie Broccardo
Vladislav Chizhevsky ,
MD SSBBP
James Wells ,
Senior Reliability Engineer, Leica Biosystems
Thomas Lee ,
MD, PhD, Director of Surgical Pathology Services, NeoGenomics Laboratories, Inc.
Sally Agersborg ,
MD, PhD, Medical Director, NeoGenomics Laboratories, Inc.

This white paper evaluates ways to scale up digital pathology operations to keep up with increasing demand, assessing the performance of the Aperio GT 450 versus Aperio AT2.

High-Resolution Episcopic Microscopy (HREM) using the HistoCore NANOCUT R Rotary Microtome by Leica Biosystems

This white paper highlights how performing automated sections using the Leica HistoCore NANOCUT R microtome led to increased reproducibility of key parameters, like the cutting surface and precise positioning of the block, leading to perfect alignment of the sections, and enhanced quality of 3D reconstructions.

Strategies for Spatial Multi-omics: Co-detection of protein and RNA biomarkers on a single FFPE tissue section powered by InSituPlex® Technology

Gourab Chatterjee ,
Associate Director of Research and Development, Ultivue Inc.
Kirsteen Maclean ,
PhD, Senior Director of Biomarker and Translational Strategy, Ultivue Inc.
Michael Sismour
Mael Manesse

This white paper highlights the value of an integrated ISP-in situ hybridization (ISH) workflow for co-detection of protein and RNA targets on a single FFPE tissue section.