Articles

This article is the first of a 4-part series including the following topics: “What is life science” (current feature), “Translational Research,” “Spatial Research,” and “Biomarkers in Translational/Spatial Research.

Learn more about tissue processing artifacts, what is "optimal" and what is "not," and how to optimize tissue processing techniques with a downloadable checklist for success.

Learn more about Immunohistochemistry (IHC) and future applications in translational research.

In this new and fully interactive eBook, learn about automated approaches to immunohistochemistry, in situ hybridiztion, whole slide digitization, and find out how they can be adopted to accelerate research programs. The document contains step-by-step guidance and top tips on implementing and validating automated systems, as well as covering key considerations to help guide you through the process.

Learn more about multiplexing and explore these educational videos and infographics to understand how to choose chromogen colors for multiplex, as well as the different detection systems available for multiplex assays. 

H&E is an important tool for disease research and drug development and is being increasingly combined with digital pathology technology. Image quality is important for slide digitization to ensure that interpretation is accurate. Take a look at some images here, produced by our digital pathology scanners.

In the webinar Cryosectioning 101 for Research, John Stock provided a comprehensive guide on achieving better cryosectioning outcomes. John went on to answer customer questions at the end of the session, that have been compiled for your viewing here.

Drug development is a timely and costly process, with the average cost of bringing a single new drug to market costing $1.3 billion, taking anywhere between 10-15 years to finalize complete all clinical trials. Preclinical studies are the vital first steps in research and development and is estimated to cost $7M over 73 months. Up to 35% of drugs are eliminated at phase I and II clinical trials due to toxicity.

Following our 2-part webinar series of Tips & Tricks to Better Histology, questions about histology-related issues were received from customers and answered by Leica Biosystems. Here, in Histology Tips & Tricks: Questions and Answers, Part 2, more questions are answered, specifically regarding decalcifying agents, and tissue section bubbling/cracking.

Multiplexing is an important tool for simultaneous detection of multiple markers within a single tissue section. These educational infographics highlight the 5 key reasons to multiplex, as well as the main considerations for choosing chromogenic or immunofluorescent detection.