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  • HistoCore NANOCUT R Person Knife Holder GD
  • HistoCore NANOCUT R Hero Left Knife Holder E TC
  • Configuration for 3D Reconstruction with NANOCUT R
  • Stacking Technique for 3D Reconstruction
  • HistoCore NANOCUT R Hero Left Knife Holder GD
  • HistoCore NANOCUT R Person Knife Holder GD
  • HistoCore NANOCUT R Hero Left Knife Holder E TC
  • Configuration for 3D Reconstruction with NANOCUT R
  • Stacking Technique for 3D Reconstruction
  • HistoCore NANOCUT R Hero Left Knife Holder GD

HistoCore NANOCUT R - Automated Research & Special Applications Rotary Microtome

14052458261

Discover New Breakthroughs with an Enhanced Level of Precision and Versatility

When your microtomy involves diverse samples in order to discover new breakthroughs in your research projects, then NANOCUT R is the optimal solution for you. The new generation of microtomes from Leica Biosystems is built upon our 145+ year heritage of market-leading microtome design. From biomedical research to industrial applications, NANOCUT R can cut virtually anything you put in front of it.

  • Cut sections that can be prepared for analysis in light microscopy and electron microscopy - down to 250nm (0.25µm, semi-thin).
  • Preserve sample integrity when performing semi-thin sectioning with the Special Spindle and expanded Slow Speed Adjustment.
  • Precisely stop the sample in the object head’s optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.*
Select a configuration

*Source for Featured 3D Reconstruction Content: IGBMC, PHENOMIN, iCS

Specs

Product Specifications

General

Type: Motorized
Nominal Supply Voltage: 100 / 120 / 230 / 240 V AC
Nominal Frequency: 50/60 Hz
Maximum Power Consumption: 100 VA
Protection Class: I
Power Fuses: 2 x T3,15 AL, 250V
Pollution Degree: 2
Overvoltage Category: II
Maximum Heat Emission: 340 J/s
Operating Temperature Range: +18°C to +35°C
Temperature Range During Storage: +5°C to +50°C
Relative Humidity During Operation: 20% to Max. 80% Non-Condensing
Relative Humidity During Storage: 10% to Max. 85% Non-Condensing

Dimensions & Weight

BASIC INSTRUMENT
Width (including handwheel and coarse feed wheel): 415 mm
Depth (including waste tray): 620 mm
Height (without top tray): 295 mm
Weight (without accessories): Approx. 40 kg
CONTROL PANEL
Type: Separate control panel & in-housing integrated instrument control panel
Width: 119 mm
Depth: 193 mm
Height: 50 mm
Height (in inclined position): 81 mm
Weight (net): 0.6 kg

Microtome Performance Specs

Specimen Feed: approx. 24 mm ±1 mm
Vertical Stroke: 70 mm ±1 mm
Large Standard Clamp: 55 x 50 x 30 mm
Super Cassette Clamp: 68 x 48 x 15 mm
Motorized Sectioning Speeds: 0 - 195 mm/s ±10%
SPECIMEN RETRACTION
In Manual Sectioning Mode: 5 - 50 µm (in 5 µm increments); can be turned off
In Motorized Sectioning Mode: Speed-Dependent; can be turned off
SPECIMEN ORIENTATION
Horizontal: ± 8°
Vertical: ± 8°
SECTION THICKNESS SETTINGS
Range: 0.25 - 50 µm
Setting Values: 0.25 - 0.5 µm (in 0.25 µm increments)
0.5 - 5 µm (in 0.5 µm increments)
5 - 20 µm (in 1 µm increments)
20 - 50 µm (in 5 µm increments)
TRIMMING SECTION THICKNESS SETTINGS:
Range: 1 - 300 µm
Setting Values: 1 - 10 µm (in 1 µm increments)
10 - 20 µm (in 2 µm increments)
20 - 50 µm (in 5 µm increments)
50 - 100 µm (in 10 µm increments)
100 - 300 µm (in 50 µm increments)

Additional Specifications

Handwheel Balance System:
Handwheel Lock / Brake: 2 Mechanical Locks, 1 Electronic Brake
Safety Hand Wheel: Handle can be Centered
WASTE TRAY
Type Standard Waste Tray
Waste Tray Volume 1400 ml
SELECTABLE CUTTING MODES
Rock Mode: - with activated retraction
Single Mode:
Continuous Mode:
Step Mode:
Program Mode:
BLADE HOLDER
Type: Semi-Thin Sectioning - Knife Holder GD
Resin Sectioning - Knife Holder NZ or Knife Holder E-TC
Paraffin Sectioning: 2-in-1 Blade Holder E
North-South Movement: ± 24 mm
East-West Movement: 3 Positions
Lateral Displacement Function: via knife holder CE clamping top
SPECIAL FEATURES
Remaining Feed Indicator Visual and Acoustical
Section Counter
Section Thickness Totalizer
Memory Position
Special Spindle for Precise Semi-Thin Sectioning
Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning
Precise 3D Object Head Stop Position

Features

Product Features

Precise and Consistent Semi-Thin Sectioning

Avoid destruction of samples with the Special Spindle and expanded Slow Speed Adjustment capabilities which allow you to produce consistent semi-thin sections down to 250nm.

HistoCore_NANOCUT_R_Hero_Front_Knife_Holder_GD
HistoCore_NANOCUT_R_Hero_Front_Knife_Holder_NZ

Tackle the Toughest Materials with a Wide Range of Accessories

Leverage a wide range of accessories available to the NANOCUT R, including holders for disposable steel and tungsten carbide blades, reusable knives, and a special holder for glass and diamond knives.

3D Reconstruction Stacking Technique

Precisely stop the sample in the object head's optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.

csm_3d-reconstruction
HistoCore_NANOCUT_R_Knife_Holder_E_TC_Orientation

Precision-Orientation System

Always get back to a 0-position home on the microtome, regardless of how you (or another tech) have changed the instrument's orientation.

 

Force Balance System

Minimize the risk of injury to the operator or specimen by an unbalanced object head.

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Currently viewing

Type Mechanical Semi-Motorized Motorized Motorized
Precision-Orientation System
Force Balance System
2-in-1 Blade Holder
Specimen Cooling Option with RM CoolClamp
Standard Waste Tray
Silent Retraction
Personalized Coarse Feed Wheel
Fast Homing
Memory Position
Electronic Brake
Special Spindle for Precise Semi-Thin Sectioning
Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning
Precise 3D Object Head Stop Position

Resources

Resources

Product Feature Demo Videos

Force Balance System

Electronic Brake

Nanocut R instrument

Frequently Asked Questions

HistoCore Microtomes

Does the new HistoCore RM antistatic tray fit on the older RM22xx series?

No – the microtome base plates of both series have different dimensions and are not compatible with each other.

How does the new antistatic waste tray reduce contamination?

The antistatic waste tray is made from resistant antistatic material to avoid debris sticking to the walls of the tray.

Is the new 2-in-1 blade holder compatible as a whole assembly with the older RM22xx series?

Yes – only in the combination blade holder and 2-in-1 blade holder.

Can we still use the backlighting with the new blade holder base for the 2-in-1 blade holder?

No – the 2-in-1 blade holder base does not have the cut-out for the backlighting.

Which accessories of the older RM22xx Series cannot be used with the HistoCore RMs anymore?

  1. Small section waste tray
  2. Large section waste tray
  3. Top tray – HistoCore RM top tray is 40% larger than the RM22xx series tray
  4. Cooling Device – too small to be placed on instrument top. However, it’s still good to place next to the instrument

 

 

What is the advantage of the personalized coarse feed wheel?

Convenience and ease-of-user – users can select their personal preference of coarse feed wheel turn direction. This feature is preserved from the RM22xx series, allowing users to trim at the high pace.

What is the advantage of “Fast homing”?

The return speed of the object head from front to home position has been reduced from 26 seconds (older series) to 13 seconds (new series). This accelerated speed helps to shorten the sectioning process each time the object head is returned to home position.

What is the advantage of the Memory Position?

When batch trimming and using the same height of blocks, Memory Position will help to accelerate the sectioning.

  1. First insert a new block
  2. Bring the block to the blade
  3. Set the Memo position (stored)
  4. Trim
  5. Remove block for re-cooling
  6. Press “Memo” – the object head returns to the set object change position
  7. Insert a new block – check position
  8. Trim again

 

 

Configurations

Configurations

Choose your option below, and then use the Contact Us link above to submit a quote request for your selection

Basic Instrument (14052458261)

  • Rotary microtome with Automated and Manual Modes
  • Automatic Electronic Brake
  • Special Spindle and expanded slow speed adjustment capabilities allows accurate specimen feeding for semi-thin sections of 250 nm
  • Precise 3D object head stop position allows for taking pictures of the cut specimen surface after each section to enable 3D reconstruction
  • Includes standard waste tray and top tray