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Difficult Blocks and Reprocessing

Difficult Blocks and Reprocessing

What To Do When Your Block Won’t Section

From time to time, in all histopathology laboratories, paraffin blocks will be encountered that are difficult or even impossible to section. This download provides guidance on how to deal with these difficult blocks to get the best possible section, and how to identify and avoid a repeat of underlying causes.

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Contents

Part 1: The initial assessment - why is my block difficult or impossible to cut?

Part 2: Getting more information: examples of typical problems and their causes

Part 3: Detailed solutions for problem blocks

Part 4: The root cause of processing problems and their prevention

Part 5: How to validate a reprocessing method

Part 6: Appendix

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