Pathologists use various stains to help make their diagnoses. One of the categories of stains is called special stains and refers to a technique where dyes or chemicals are used to identify specific cell structures or components present within the submitted sample. The pathologist can use these particular special stains to confirm or categorize the potential diagnoses.
Connective tissue plays an essential role in the human body by holding together, protecting, supporting, and joining organs to tissues. This editorial describes the categories of connective tissue, the types of connective tissue diseases, and the diagnosis of connective tissue diseases.
BS Biology, HT, Advanced Technical Lead at Leica Biosystems
Practicing sustainability in the histology laboratory shapes paradigms in four fundamental ways: minimizing our impact on the Earth, maintaining our well-being, decreasing the cost of waste management in the laboratory, and discovering new processes affecting our daily work.
Current technology allows tumors to be painted with multiple colors, termed multiplex staining. Multiplex staining today used in research, may also assist with cancer diagnoses clinically via: preservation of tissue, improved diagnostic accuracy, and enhanced diagnostic insight.
Cytogenomics is the study of genetics that studies chromosomes and their relation to diseases. Through a combined analysis of chromosomes and molecular tests, clinicians can better understand and treat disease states.
Varying the approach angle in stereotaxic surgery can overcome the conflict between positional accuracy and interpretability. Fortunately, modern computer controlled stereotaxic instruments make this possible.
As well as formaldehyde and glutaraldehyde, discussed previously, a number of other reagents have been used for fixation, sometimes in simple solution but often combined with other agents in the form of compound fixatives. The more important of these are...