Aperio FL Scanning Systems - Flexible, Brightfield, Fluorescent, and FISH Scanners

The Flexibility You Need – The Quality You Deserve

Complex research drives the breakthroughs that transform patient care. The Aperio FL Scanning Systems are purpose-built to support this mission—delivering robust, high-performance digital pathology solutions with Excellent Image Quality, Extensive Flexibility and Exceptional Ease-of-use to meet the demands of today’s most advanced translational research environments.

Aperio FL Scanning Systems:

Aperio FL 120: Ideal for large-scale research programs and high-throughput environments.
Aperio FL 10: Perfectly suited for smaller studies and focused investigations.

Both systems feature:

One-click operation for rapid, reproducible slide digitization
Intuitive interface designed for ease-of-use across diverse teams
Comprehensive functionality to adapt to evolving research needs

As the global leader in digital pathology, with over 25 years of innovation, more than 450 image capture technology patents, and a distinction of quality using world-renown Leica objectives, we empower your lab to deliver results with confidence.

For Research Use Only. Not for Use in Diagnostic Procedures.

Aperio FL Scanning Systems Features

Excellent Image Quality

Effortless Scanning. Exceptional Results.

150 Years of Leica Optical Excellence - Built on a legacy of German engineering, delivering unmatched clarity and detail
Next-Gen Fluorescence Camera - Reduced noise, enhanced detection of low-light fluorescent signals, and superior signal-to-background clarity
Reproducibility of Results - Minimize variability and enable consistent, reproducible scanning across studies
Publication-Ready Images - Maximize the visual impact of figures in scientific publications and presentations

Extensive Flexibility

Aperio FL scanning systems—where usability meets precision, and innovation meets flexibility.

Highly Flexible Imaging Platform A broad wavelength range from 360–770 nm, 8-slot automatic filter wheel, and per-channel adjustable LED light intensity, delivers full control to optimize your 7-channel fluorescent multiplex imaging
Fine-tune imaging parameters to meet the specific needs of your Brightfield, Fluorescence, or FISH research
Dynamically adjust magnification ranges for optimal resolution and field of view
Optimize fluorescence channels to capture precise, high-quality images

Exceptional Ease of Use

Produce high-quality digital slides in just minutes

Quick Onboarding - Even novices can begin scanning their own slides within 10 minutes of introduction
Intuitive Interface - Users to review high-quality fluorescence images almost immediately
Instant Data Portability - Export scanned images and analysis results right after use
Simplicity in Operation - Focus on discovery—not device complexity

One System. Endless Possibilities.

Whether you're conducting biomarker discovery, elucidating disease mechanisms, or exploring the tumor microenvironment, the Aperio FL scanning system offers multi-modal whole slide imaging—including brightfield, fluorescence, and FISH—in a single, streamlined system. With high magnification oil scanning and superior Leica optics, every detail is captured with clarity and precision.

Brightfield Applications:

Biomarkers
TMA
Oncology
Toxicology
Animal studies
Infectious diseases
Neurological
Machine learning

Fluorescence Applications:

Spatial proteomics
Biomarkers
Oncology
Toxicology
Animal studies
Infectious diseases
Neurological
Circulatory

Optional Extras:

Automatic Oiler for 40x and 63x oil immersion scanning
Additional objectives: 20x, 40x, 63x (System includes 1.25x, 5x, and 10x)
Dichroic filter selection
Fluorescent calibration slides

Fluorescence and Brightfield Scanning Gallery

Lung Cancer Tissue

Shown at 20x magnification.

View High Resolution Slide

Colorectal Cancer Tissue

Shown at 20x magnification.

View High Resolution Slide

Breast Cancer Tissue

Shown at 63x Oil magnification.

View High Resolution Slide

Breast Cancer Tissue

Colon-Cancer-Tissue-T2-0074B1-Breast-20x-0221-2-750x454

Shown at 20x magnification.

TMA

View High Resolution Slide

Breast Cancer Tissue

Oil-Tissue-FISH-DGG-T2-253B3-CK-40x-0220-4

Shown at 40x magnification.

View High Resolution Slide

Product Specifications

Aperio FL Scanning Systems Specifications

Slide Loader	10 or 120 slide capacity; Automatic slide loading by tray, 5 slides per tray.
Image Resolution	BF 2048x2048, 5.5×5.5μm pixel size FL 2048x2048, 6.5x6.5um pixel size sCmos with 82%(max) Quantum Efficiency.
Leica DM 6B Microscope	8-slot automatic FL filter wheel 7-slot automatic objective nosepiece, supported objective to maximum 63x and 40x/63x Oil Lens X-Cite LED Extra long lifetime FL light source with liquid light guide.
Scanning	Fully automated scanning and interactive scanning Tissue Finder: Aperio FL provides tissue finder, coverslip finder, tissue finder inside coverslip and FL tissue finder for users to choose from. Z-stack: Aperio FL support capturing multiple images at different focal planes to create a 3D representation of a specimen. BF support 0.1um-20um steps and up to 10 layers. FL supports 0.1um-3um steps and up to 25 layers. FISH enhancement: Aperio FL support probe deconvolution to removes background fluorescence. Scan speed: BF 15x15mm 20x: 359s FL 10x10mm 20x 3-channel: 15m; FL 10x10mm 20x 6-channel: 26m