Chromogenic Multiplex Biomarker Profiling of Human FFPE Tissues Using UltraPlex Technology
Cell IDx’s UltraPlex chromogenic multiplex IHC technology allows the chromogenic detection of 3-4 markers simultaneously on a single tissue section using standard industry workflows. The protocol has been developed to run on the BOND RX autostainer using a single antigen retrieval step and is completed in ~4.5 hours. Adding to its broad utility, BOND RX the technology is primary antibody species independent. Images are obtained on all brightfield scanners in 5-15 minutes. This tissue conserving technology provides maximal information on small tissue samples. FFPE tissue-optimized panels for key biomarkers are available and other panels can be developed on request.
- Learn how UltraPlex chromogenic multiplex IHC technology allows detection of multiple cell subtypes co-expressing multiple biomarkers using optimized chromogen combinations.
- Learn how to expedite your data generation using a simple, fast, streamlined process combining UltraPlex chromogenic multiplex IHC panels with staining on the BOND RX staining platform and Aperio brightfield scanners.
- Learn how to increase data generation from limited FFPE tissue samples including TMAs using this tissue conserving technology.
For the use of any product, the applicable product documentation, including information guides, inserts and operation manuals should be consulted.
Copyright © 2024 Leica Biosystems division of Leica Microsystems, Inc. and its Leica Biosystems affiliates. All rights reserved. LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.