Warning! You won't be able to use the quotation basket until you enable cookies in your Web browser.
Warning! Your Web browser is no longer supported. Please upgrade to a modern browser.

Quantitative and Automated Analysis in Molecular Pathology

Overview

Recent advances in chemistry has resulted in a surge in the application of RNA ISH and DNA FISH assays in pathology. These molecular assays do offer numerous advantages over traditional IHC staining. However, due to multiplex assays and the sophistication of the scoring system used, molecular assays can be difficult to assess using a traditional microscope. Digital Pathology offers numerous advantages over traditional microscope based reviews, including the generation of a permanent record of the slide, the ability to share slides with colleagues in remote locations and the option of using software to assist in the assessment of the staining. Automated image analysis can be used to quantify and enumerate RNA and DNA Brightfield and fluorescently captured slides. Within this presentation, we will discuss the advantages and applications using image analysis as an adjunct to manual interpretation of molecular assays.

Learning Objectives:

  1. Review of Molecular Assay Approaches.
  2. Overview of the advantages of Digital Pathology and Image analysis when reviewing molecular assays.
  3. Discuss the capabilities in the area of digital pathology and quantitative image analysis.

Leica Biosystems webinars, training presentations and related materials provide general information regarding particular subjects and are not intended to be, and should not be construed as medical, regulatory or legal advice. The views and opinions expressed are the personal views and opinions of the speaker(s)/author(s) and do not necessarily represent or reflect the views or opinions of Leica Biosystems, its employees or agents.

For the use of any product, the product information guides, inserts and operation manuals of the various products and devices should be consulted. Leica Biosystems and the editors disclaim any liability arising directly or indirectly from the use of devices, techniques or procedures described in these materials.

Copyright © 2016 by Leica Biosystems Richmond Inc. All rights reserved.LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.