Antigen Backgroundp40 (Delta Np63) is a truncated product of the p63. It is normally expressed in the basal or progenitor cell layer of stratified epithelia, basal cells of prostate, as well as myoepithelial cells of breast and salivary glands, and cytotrophoblasts in placenta, and shows a nuclear staining pattern with IHC. Among the numerous neoplasms positive for p40, squamous cell carcinomas of pulmonary and non-pulmonary origin can be identif...

Biomarkers AE1/AE3 AMACR BCL6 CD20 CD3 CD4 CD68 CD8 CDX2 CK20 Ck5 Colocalization Counterstain ...

It’s Time for TIME Alexander “Sandy” Borowsky Professor of Pathology and Laboratory Medicine Center for Immunology and Infectious Diseases Disclosures Bristol-Meyers Squibb/Celgene: Funded through Investigator Sponsored Research (ISR) program. Discovery proposal. Leica/Aperio: Funded to run the “Genesis” study for primary diagnosis from whole slide images. Honorarium for this presentation. Histolix: Slide-free histology (Levenson and Fereidouni). Pfizer: Pfizer Protocol A9001502, Treatment Resistance Following Therapies (TRANSLATE) site PI. Agenda: In contracting to join the “FLEX” registry. None of these has actually paid me, only funding for the research projects. Objectives • Introduction into the complexity of the TIME and the development of new cancer treatments though di...