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Grant writing is a critical part of an investigator’s portfolio. Download this helpful resource for tips and tricks on how to write a grant proposal.
VISTA, CA – January 7th, 2019 – Leica Biosystems, the global leader in pathology workflow solutions announced today that the US Patent Office has granted it a patent for RTF, its breakthrough “Real-Time Focusing” technology (US patent 9,841,590). This will enable high volume, extremely fast line scanning of anatomic pathology slides.
“RTF technology dramatically improves slides scanning speed while delivering excellent optical focus. Extremely short scan times can now be achieved at 40x magnification,” said Jerome Clavel, General Manager of Leica Biosystems Pathology Imaging. “We have been working internally with RTF technology for quite some time. We will be integrating and commercializing RTF into our next-generation digital pathology platform shortly.”
Leica Biosystems has b...
Introduction to immuno oncology
1. Introduction to Immuno-Oncology Michael Bates, MD Oncology Strategy, Medical and Scientific Affairs Cepheid Sunnyvale, CA Cepheid and Leica Biosystems are Danaher Companies
2. Overview • History of Immuno-Oncology • Types of Immunotherapy • Immunomodulatory agents • Personalized Cancer Vaccines • CAR-T cell therapy • Immune Checkpoint Inhibitors • Focus: Immune Checkpoint Biomarkers
3. Evolution of Cancer Immunotherapy • William Coley – 1890s surgeon • Coley’s toxin… • BCG, IFN-alpha, IL-2 • IL-2 applications in melanoma and RCC proved that advanced metastatic cancers can be controlled in some patients by stimulating T cells with cytokines • Critical development • CTLA-4 shown to be inhibitory for T cell responses by James Allison and Jeff Blu...
Dr. Saba Nayar is an experienced Research Scientist with a history of working in Immunology Research and Project Management. She is skilled in Writing Grants, Team Management, Project Management, Multi-color Flow Cytometry, Assay Development, ELISA, Laser Capture Microdissection, and NGS. Dr. Nayar has a Doctor of Philosophy - Ph.D. focused on Immunity and Infection from the University of Birmingham.
It’s Time for TIME Alexander “Sandy” Borowsky Professor of Pathology and Laboratory Medicine Center for Immunology and Infectious Diseases
Disclosures Bristol-Meyers Squibb/Celgene: Funded through Investigator Sponsored Research (ISR) program. Discovery proposal. Leica/Aperio: Funded to run the “Genesis” study for primary diagnosis from whole slide images. Honorarium for this presentation. Histolix: Slide-free histology (Levenson and Fereidouni). Pfizer: Pfizer Protocol A9001502, Treatment Resistance Following Therapies (TRANSLATE) site PI. Agenda: In contracting to join the “FLEX” registry. None of these has actually paid me, only funding for the research projects.
Objectives • Introduction into the complexity of the TIME and the development of new cancer treatments though di...
Producing an H&E stained slide is a process. It starts way before the slide is loaded on a stainer or moved down through containers by hand. Producing quality, consistent and reproducible H&E stained slides is a process as well as a lesson in...
Processing multiple specimen and performing serial cuts can result in high section numbers. Nevertheless, reproducibility can't be compromised. Permanent attention to detail and many hours in front of the cryostat can be exhausting for the user. The Leica CM3050 S cryostat is designed to help with exactly these time-consuming jobs.
The low working height and available knee space of the Leica CM3050 S cryostat allow the user to work comfortably while sitting. Motorized drive and section counter improve productivity for multiple serial sections.
Particularly when working with delicate specimens, e.g. brain samples, the precise specimen orientation and the specimen feed system provide for reproducible sections.