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Peer-Reviewed Publications Repository - BOND RX

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CAR RNA FISH assay to study functional and spatial heterogeneity of chimeric antigen receptor T cells in tissue

Publication Year: 2021
Country: USA
PMID: N/A
Publication: Scientific Reports. 2021;11(1). doi:10.1038/s41598-021-96979-0
Institute: Fred Hutchinson Cancer Research Center, University of Washington, Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute

Instrument:

BOND RX
Authors: Eichholz K, Li AZ, Diem K, Jensen MC, Zhu J, Corey L. A
Study Goals: A CAR RNA FISH histo-cytometry platform combined with a random reaction seed image analysis algorithm to quantitate spatial distribution and in vivo functional activity of a CAR T cell population at a single cell resolution for preclinical models.
Keywords: BOND RX, Chimeric antigen receptor, (CAR) T, CAR RNA FISH, histo-cytometry
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A non-clinical comparative study of IL-23 antibodies in psoriasis

Publication Year: 2021
Country: USA
PMID: 34460338
Publication: mAbs. 2021;13(1). doi:10.1080/19420862.2021.1964420
Institute: Abbvie Bioresearch Center, Worcester

Instrument:

BOND RX
Authors: Zhou L, Wang Y, Wan Q, et al.
Study Goals: To investigate if four clinically approved antibodies targeting IL-23 differ in affinity and binding epitope
Keywords: BOND RX, IL-23, IL-12, psoriasis, autoimmune disease, risankizumab, guselkumab, tildrakizumab, ustekinumab
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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.

Publication Year: 2021
Country: UK
PMID: PMC8187652
Publication: Nature Communications. 2021;12(1). doi:10.1038/s41467-021-23717-5
Institute: Cancer Research UK Beatson Institute, Glasgow

Instrument:

BOND RX
Authors: Leach JDG, Vlahov N, Tsantoulis P, et al.
Study Goals: To study a mouse model of right-sided colon cancer driven by oncogenic BRAF and loss of epithelial TGFβ-receptor signalling
Keywords: BOND RX, colorectal cancer, oncogenic BRAF, epithelial TGFβ-receptor signaling, RNAscope, Multiplex

Feasibility of administering human pancreatic cancer chemotherapy in a spontaneous pancreatic cancer mouse model.

Publication Year: 2021
Country: USA
PMID: PMC8848646
Publication: BMC Cancer. 2022;22(1). doi:10.1186/s12885-022-09255-3
Institute: Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Instrument:

BOND RX
Authors: Delahoussaye AM, Abi Jaoude J, Green M, et al.
Study Goals: To demonstrate the utility and feasibility of clinically relevant mFOLFIRINOX and gemcitabine/nab-paclitaxel in preclinical models of pancreatic cancer.
Keywords: BOND RX, Gemcitabine; KPC mice; Nab-paclitaxel; Pancreatic cancer; SBRT; mFOLFIRINOX

Stemness-Associated Markers Are Expressed in Extracranial Arteriovenous Malformation.

Publication Year: 2021
Country: New Zealand
PMID: PMC8017302
Publication: Frontiers in Surgery. 2021;8. doi:10.3389/fsurg.2021.621089
Institute: Gillies McIndoe Research Institute, Wellington

Instrument:

BOND RX
Authors: Luke Krishnan CS, Brasch HD, Patel J, et al.
Study Goals: Investigated the presence and expression pattern of OCT4, SOX2, NANOG, KLF4, and c-MYC in extracranial AVM
Keywords: BOND RX

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