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Leica RM CoolClamp Improved workflow and uniform paraffin sections

Improve the workflow at your microtome by using the RM CoolClamp, the electrically cooled universal cassette clamp for the RM2200 Rotary Microtomes.

Keep blocks longer cold and continuously cut uniform sections.The RM CoolClamp mounts easily to any RM2200 series microtome and maintains blocks temperature at 20 °C below ambient. With each block held at the ideal temperature, you’ll find it a breeze to cut high-quality sections for routine, special and IHC/ISH staining.

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Specs

Features

Product Features

No re-cooling necessary after trimming

The energy efficient cooling device with air vent system allows specimen trimming and sectioning without time consuming specimen re-cooling prior to section collection. This allows to continuously cut uniform sections.

Remove the heat

The RM CoolClamp prevents fast heating up of the specimen during trimming and keeps it at 20 °C lower than the ambient temperature – e.g., at a room temperature of 20 °C the specimen is cooled to 0 °C.

Uniform sections – all day long

Uniform section quality and section thickness is the result of the controlled specimen temperature. The RM CoolClamp improves efficiency and versatility and is the ideal solution for modern high-productivity laboratories.

An ideal combination

All RM2200 Rotary Microtomes can be retrofitted with the RM CoolClamp without hand wheel modification.

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Documents

Documents

Brochures

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Certificates

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Material Safety Data Sheets

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User Manuals/IFUs

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Resources

Resources

Product Feature Demo Videos

Leica RM CoolClamp Tutorial

Leica RM CoolClamp Tutorial

Antigen Processing and MHC-II Presentation by Dermal and Tumor-Infiltrating Dendritic Cells

Michael Y. Gerner and Matthew F. Mescher
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2 - Antigen Processing and MHC-II Presentation by Dermal and Tumor-Infiltrating Dendritic Cells
Michael Y. Gerner and Matthew F. Mescher
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Frequently Asked Questions

HistoCore Microtomes

Does the new HistoCore RM antistatic tray fit on the older RM22xx series?

No – the microtome base plates of both series have different dimensions and are not compatible with each other.

How does the new antistatic waste tray reduce contamination?

The antistatic waste tray is made from resistant antistatic material to avoid debris sticking to the walls of the tray.

Is the new 2-in-1 blade holder compatible as a whole assembly with the older RM22xx series?

Yes – only in the combination blade holder and 2-in-1 blade holder.

Can we still use the backlighting with the new blade holder base for the 2-in-1 blade holder?

No – the 2-in-1 blade holder base does not have the cut-out for the backlighting.

Which accessories of the older RM22xx Series cannot be used with the HistoCore RMs anymore?

  1. Small section waste tray
  2. Large section waste tray
  3. Top tray – HistoCore RM top tray is 40% larger than the RM22xx series tray
  4. Cooling Device – too small to be placed on instrument top. However, it’s still good to place next to the instrument

 

 

What is the advantage of the personalized coarse feed wheel?

Convenience and ease-of-user – users can select their personal preference of coarse feed wheel turn direction. This feature is preserved from the RM22xx series, allowing users to trim at the high pace.

What is the advantage of “Fast homing”?

The return speed of the object head from front to home position has been reduced from 26 seconds (older series) to 13 seconds (new series). This accelerated speed helps to shorten the sectioning process each time the object head is returned to home position.

What is the advantage of the Memory Position?

When batch trimming and using the same height of blocks, Memory Position will help to accelerate the sectioning.

  1. First insert a new block
  2. Bring the block to the blade
  3. Set the Memo position (stored)
  4. Trim
  5. Remove block for re-cooling
  6. Press “Memo” – the object head returns to the set object change position
  7. Insert a new block – check position
  8. Trim again

 

 

Configurations