Leica RM CoolClamp Improved workflow and uniform paraffin sections
Improve the workflow at your microtome by using the RM CoolClamp, the electrically cooled universal cassette clamp for the RM2200 Rotary Microtomes.
Keep blocks longer cold and continuously cut uniform sections.The RM CoolClamp mounts easily to any RM2200 series microtome and maintains blocks temperature at 20 °C below ambient. With each block held at the ideal temperature, you’ll find it a breeze to cut high-quality sections for routine, special and IHC/ISH staining.
No re-cooling necessary after trimming
The energy efficient cooling device with air vent system allows specimen trimming and sectioning without time consuming specimen re-cooling prior to section collection. This allows to continuously cut uniform sections.
Remove the heat
The RM CoolClamp prevents fast heating up of the specimen during trimming and keeps it at 20 °C lower than the ambient temperature – e.g., at a room temperature of 20 °C the specimen is cooled to 0 °C.
Uniform sections – all day long
Uniform section quality and section thickness is the result of the controlled specimen temperature. The RM CoolClamp improves efficiency and versatility and is the ideal solution for modern high-productivity laboratories.
An ideal combination
All RM2200 Rotary Microtomes can be retrofitted with the RM CoolClamp without hand wheel modification.
|95.9744 Rev B Flyer RM CoolClamp EN||(PDF)|
|95.9745 Rev B Flyer RM CoolClamp DE||(PDF)|
|95.9746 Rev B Flyer RM CoolClamp FR||(PDF)|
|95.9747 Rev B Flyer RM CoolClamp ES||(PDF)|
|95.9748 Rev B Flyer RM CoolClamp IT||(PDF)|
|EU Declaration Leica RM CoolClamp A en||(PDF)|
Material Safety Data Sheets
|Oil for drives. Typ Constant OY 46 K 50ml 14033606086 Rev.01 GB||(PDF)|
|RM CoolClamp IFU 1v1B cs||(PDF)|
|RM CoolClamp IFU 1v1B da||(PDF)|
|RM CoolClamp IFU 1v1B de||(PDF)|
|RM CoolClamp IFU 1v1B en||(PDF)|
|RM CoolClamp IFU 1v1B es||(PDF)|
|RM CoolClamp IFU 1v1B fi||(PDF)|
|RM CoolClamp IFU 1v1B fr||(PDF)|
|RM CoolClamp IFU 1v1B hu||(PDF)|
|RM CoolClamp IFU 1v1B it||(PDF)|
|RM CoolClamp IFU 1v1B ja||(PDF)|
|RM CoolClamp IFU 1v1B ko||(PDF)|
|RM CoolClamp IFU 1v1B lt||(PDF)|
|RM CoolClamp IFU 1v1B nl||(PDF)|
|RM CoolClamp IFU 1v1B no||(PDF)|
|RM CoolClamp IFU 1v1B pl||(PDF)|
|RM CoolClamp IFU 1v1B pt||(PDF)|
|RM CoolClamp IFU 1v1B ru||(PDF)|
|RM CoolClamp IFU 1v1B sk||(PDF)|
|RM CoolClamp IFU 1v1B sr||(PDF)|
|RM CoolClamp IFU 1v1B sv||(PDF)|
|RM CoolClamp IFU 1v1B tr||(PDF)|
|RM CoolClamp IFU 1v1B zh||(PDF)|
Product Feature Demo Videos
Antigen Processing and MHC-II Presentation by Dermal and Tumor-Infiltrating Dendritic Cells
Michael Y. Gerner and Matthew F. Mescher
Go to publication
2 - Antigen Processing and MHC-II Presentation by Dermal and Tumor-Infiltrating Dendritic Cells
Michael Y. Gerner and Matthew F. Mescher
Go to publication
Frequently Asked Questions
Does the new HistoCore RM antistatic tray fit on the older RM22xx series?
No – the microtome base plates of both series have different dimensions and are not compatible with each other.
How does the new antistatic waste tray reduce contamination?
The antistatic waste tray is made from resistant antistatic material to avoid debris sticking to the walls of the tray.
Is the new 2-in-1 blade holder compatible as a whole assembly with the older RM22xx series?
Yes – only in the combination blade holder and 2-in-1 blade holder.
Can we still use the backlighting with the new blade holder base for the 2-in-1 blade holder?
No – the 2-in-1 blade holder base does not have the cut-out for the backlighting.
Which accessories of the older RM22xx Series cannot be used with the HistoCore RMs anymore?
- Small section waste tray
- Large section waste tray
- Top tray – HistoCore RM top tray is 40% larger than the RM22xx series tray
- Cooling Device – too small to be placed on instrument top. However, it’s still good to place next to the instrument
What is the advantage of the personalized coarse feed wheel?
Convenience and ease-of-user – users can select their personal preference of coarse feed wheel turn direction. This feature is preserved from the RM22xx series, allowing users to trim at the high pace.
What is the advantage of “Fast homing”?
The return speed of the object head from front to home position has been reduced from 26 seconds (older series) to 13 seconds (new series). This accelerated speed helps to shorten the sectioning process each time the object head is returned to home position.
What is the advantage of the Memory Position?
When batch trimming and using the same height of blocks, Memory Position will help to accelerate the sectioning.
- First insert a new block
- Bring the block to the blade
- Set the Memo position (stored)
- Remove block for re-cooling
- Press “Memo” – the object head returns to the set object change position
- Insert a new block – check position
- Trim again
|Code||Name Show all details||Qty|
Leica RM CoolClamp
Electrically Cooled Universal Cassette Clamp with Adapter
for Leica RM2200 and HistoCore Rotary Microtome Series
Microtome produces uniform sections due to electrically
cooled universal cassette clamp with the Leica RM CoolClamp.
Energy efficient cooling with air removal by air vent system.
The unique balance system on the Leica RM2200 and HistoCore
rotary microtome series means convenient and safe specimen clamp
exchange without requiring modification of the hand wheel.
Retrofits to all rotary microtomes of the Leica RM2200 and
HistoCore Rotary Microtomes Series.
Please note: RM CoolClamp cannot be used with
microscope or magnifier.
Pre-cooling prior to work start: 30 minutes
Temperature: 20 K less than ambient
Ambient temperature range: 10 °C to 35 °C
Humidity: max 80 %, non condensing
Weight: approx. 650 g
Dimensions (D x W x H): 80 x 114 x 204 mm
Mains power supply: 100 - 240 V /50/60Hz
Approvals: CE, c_CSA_US
Power supply with cable and 4 adapters (UK, US, EU, AUS)
5 cable clips
Instructions for use and DVD