INTRODUCING THE BOND MMR ANTIBODY PANEL
Interpretation Guide
Lynch Syndrome is associated with a 50-70% lifetime risk of colorectal cancer (CRC) and an increased risk of other malignancies therefore identification of such high-risk patients is vital.
Accuracy Study
The results of this study provide a comparison of the IHC staining profiles generated by the BOND MMR Antibody Panel and results of NGS analysis for a set of 137 CRC FFPE tissue samples.
Fast. Efficient. Accurate.
View exceptional quality stains from the BOND MMR Antibody Panel focusing on three case outcomes with positive and negative slides for all markers.
Name : Case A MLH1
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MLH1 (Mismatch Repair Protein) (ES05) PA0988-U
Protein Expression : Intact
Name : Case A MSH2
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MSH2 (Mismatch Repair Protein) (79H11) PA0989-U
Protein Expression : Loss
Name : Case A MSH6
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MSH6 (Mismatch Repair Protein) (EP49) PA0990-U
Protein Expression : Loss
Name : Case A PMS2
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : PMS2 (Mismatch Repair Protein) (EP51) PA0991-U
Protein Expression : Intact
Name : Case B MLH1
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MLH1 (Mismatch Repair Protein) (ES05) PA0988-U
Protein Expression : Loss
Name : Case B MSH2
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MSH2 (Mismatch Repair Protein) (79H11) PA0989-U
Protein Expression : Intact
Name : Case B MSH6
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MSH6 (Mismatch Repair Protein) (EP49) PA0990-U
Protein Expression : Intact
Name : Case B PMS2
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : PMS2 (Mismatch Repair Protein) (EP51) PA0991-U
Protein Expression : Loss
Name : Case C MLH1
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MLH1 (Mismatch Repair Protein) (ES05) PA0988-U
Protein Expression : Intact
Name : Case C MSH2
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MSH2 (Mismatch Repair Protein) (79H11) PA0989-U
Protein Expression : Intact
Name : Case C MSH6
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : MSH6 (Mismatch Repair Protein) (EP49) PA0990-U
Protein Expression : Intact
Name : Case C PMS2
Tissue : Bowel Adenocarcinoma
IHC Primary Antibody : PMS2 (Mismatch Repair Protein) (EP51) PA0991-U
Protein Expression : Intact
FOR IN VITRO DIAGNOSTIC USE ONLY