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Our Innovation Partners

Access the Latest Research Advances

Technologies partnered with a fully automated workflow yield visionary outcomes.

Leica Biosystems collaborates with diverse, cutting-edge technologies to co-develop flexible, open platforms that automate your tissue-based research workflows. Our Open Innovation (OI) partnerships enable easy integration across technologies, supporting fluorescent and chromogenic protocols. Our OI partnership collaborations bring creative solutions helping to answer your most pressing research questions.

About Our Partnerships

Innovation Meets Automation

Leica Biosystems partners with a range of Open Innovation (OI) partners. As a result, you have many flexible solutions for your research. Most protocols and protocol templates developed in conjunction with our OI partners are available on BOND RX and BOND RXm staining systems, so you can access the latest research advances quickly.

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For Research Use Only. Not for use in diagnostic procedures.

Our Global Partners 

High Plex, Spatial Profiling of Proteins and RNA from FFPE

Combining standard immunofluorescence techniques with digital optical barcoding technology, the GeoMx® Digital Spatial Profiler enables high plex, spatially-resolved profiling of protein and RNA. The GeoMx Assays allow for imaging and profiling from a single FFPE or fresh frozen tissue section.

  • Quantify with spatial context 150+ proteins and up to the whole transcriptome
  • Focus on rare cells or compartment-specific regions of interest in tissue
  • Preserve precious samples with non-destructive processing

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A Fully Integrated RNA ISH Solution

Complete up to 30 slides in a single 11-hour run for single plex (and a 14-hour run for duplex) with high-throughput staining. This solution is:

  • Highly specific – Amplifies signals using double z probe strategy and simultaneous background suppression strategy to ensure target-specific binding
  • Sensitive & Quantitative – Detects single RNA molecules at single cell resolution
  • Morphological – Provides cell specific expression in information intact tissue architecture
  • Universal – Use for virtually any gene, species or tissue

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A Fully Integrated RNA ISH Solution Partner - ACD

Single Step Multiplexing, Fully Automated

Create up to 30, five color multiplex slides in under 6 hours on BOND RX whilst preserving tissue morphology and integrity. Spend less time perfecting difficult manual techniques and more time focusing on your next research breakthrough.

  • Survey and analyze cell phenotypes with spatial context within the tumor microenvironment though high performance tissue-based biomarker multiplex assays
  • Multiplex on a single slide, using a single antibody cocktail and incubation step, powered by DNA barcoded antibodies with unique, complementary, fluorescent DNA barcodes
  • Preserve sample integrity for additional analyses without damaging tissue or cross talk
  • Image and analyze with Aperio VERSA and Aperio Cellular IF Algorithm
Multiplexing in un solo passaggio, totalmente automatico

Fully automated in situ proximity ligation assays: Naveni® kits for BOND RX/RXm

The NaveniBright and Naveni PD/PD-L1 BOND RX HRP introduce two novel products integrating chromogenic readout automation on the BOND RX and BOND RXm automated research staining platforms by Leica Biosystems. 

  • Detect protein-protein interactions and post-translational modifications efficiently using the Leica Biosystems BOND RX, ensuring high precision and accuracy
  • Visualize specific protein targets like PD1/PD-L1 while preserving intact cell and tissue morphology, providing a holistic understanding of spatial protein relationships
  • Ready-to-use kits optimized for FFPE samples and reagents sufficient for 30 FFPE tissue slides

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On-Demand Presentations

Our featured webinars showcase the power of Leica Biosystems automated solutions and partner technologies. Watch now to envision your research outcomes.

Characterization of the Pancreatic Tumor Microenvironment using Novel Quantitative Multiplex DSP

Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive disease associated with poor outcomes. So far, the factors and pathways underlying patient survival in PDAC are unknown.

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Introducing New RNA-Protein Co-Detection Assays

Learn more about ACD’s new Co-Detection Assays, which will allow researchers to simultaneously examine cell-type-specific gene expression and identify cellular sources of secreted proteins.

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Strategies for Spatial Multi-omics: Co-detection of protein and RNA biomarkers on a single FFPE tissue section powered by InSituPlex® Technology

Understanding the complexities of a particular tumor microenvironment can vastly improve the accuracy of immuno-oncology clinical prognosis and accelerate the discovery of immunotherapy targets towards patient-focused personalized medicine.

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Cutting Edge Tech: Success Stories


Implementation of Fully Automated BOND RX Protocol for NanoString's GeoMx® Assay


Automated, Multiplexed Co-detection of RNA and Protein:

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For Research Use Only. Not for use in Diagnostic Procedures.