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HistoCore NANOCUT R - Automated Research & Special Applications Rotary Microtome
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HistoCore NANOCUT R - Discover New Breakthroughs
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HistoCore NANOCUT R - Automated Research & Special Applications Rotary Microtome

14052458261

Discover New Breakthroughs with an Enhanced Level of Precision and Versatility

When your microtomy involves diverse samples in order to discover new breakthroughs in your research projects, then NANOCUT R is the optimal solution for you. The new generation of microtomes from Leica Biosystems is built upon our 145+ year heritage of market-leading microtome design. From biomedical research to industrial applications, NANOCUT R can cut virtually anything you put in front of it.

  • Cut sections that can be prepared for analysis in light microscopy and electron microscopy - down to 250nm (0.25µm, semi-thin).
  • Preserve sample integrity when performing semi-thin sectioning with the Special Spindle and expanded Slow Speed Adjustment.
  • Precisely stop the sample in the object head’s optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.*
Contact us to get a quote. Call +31 850 013726 to speak with a representative.

*Source for Featured 3D Reconstruction Content: IGBMC, PHENOMIN, iCS

For Research Use Only. Not for use in diagnostic procedures.

Product Features

Precise and Consistent Semi-Thin Sectioning

Avoid destruction of samples with the Special Spindle and expanded Slow Speed Adjustment capabilities which allow you to produce consistent semi-thin sections down to 250nm.

HistoCore NANOCUT R Hero Front Knife Holder GD

Tackle the Toughest Materials with a Wide Range of Accessories

Leverage a wide range of accessories available to the NANOCUT R, including holders for disposable steel and tungsten carbide blades, reusable knives, and a special holder for glass and diamond knives.

HistoCore NANOCUT R Hero Front Knife Holder NZ

3D Reconstruction Stacking Technique

Precisely stop the sample in the object head's optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.

3D Reconstruction Stacking Technique

Precision-Orientation System

Always get back to a 0-position home on the microtome, regardless of how you (or another tech) have changed the instrument's orientation.

HistoCore_NANOCUT_R_Knife_Holder_E_TC_Orientation

Force Balance System

Minimize the risk of injury to the operator or specimen by an unbalanced object head.

Product Specifications

GENERAL

Type: Motorized
Nominal Supply Voltage: 100 / 120 / 230 / 240 V AC
Nominal Frequency: 50/60 Hz
Maximum Power Consumption: 100 VA
Protection Class: I
Power Fuses: 2 x T3,15 AL, 250V
Pollution Degree: 2
Overvoltage Category: II
Maximum Heat Emission: 340 J/s
Operating Temperature Range: +18°C to +30°C
Temperature Range During Storage: +5°C to +50°C
Relative Humidity During Operation: 20% to Max. 80% Non-Condensing
Relative Humidity During Storage: 10% to Max. 85% Non-Condensing

DIMENSIONS & WEIGHT

BASIC INSTRUMENT  
Width (including handwheel): 415 mm
Depth (including waste tray): 620 mm
Height (without top tray): 295 mm
Weight (without accessories): Approx. 40 kg
CONTROL PANEL  
Type: Separate control panel & in-housing integrated instrument control panel
Width: 119 mm
Depth: 193 mm
Height: 50 mm
Height (in inclined position): 81 mm
Weight (net): 0.6 kg

MICROTOME PERFORMANCE SPECS

Specimen Feed: approx. 24 mm ±1 mm
Vertical Stroke: 70 mm ±1 mm
  Large Standard Clamp: 55 x 50 x 30 mm

Super Cassette Clamp: 68 x 48 x 15 mm
Motorized Sectioning Speeds: 0 - 195 mm/s ±10%
SPECIMEN RETRACTION  
In Manual Sectioning Mode: 5 - 50 µm (in 5 µm increments); can be turned off
In Motorized Sectioning Mode: Speed-Dependent; can be turned off
SPECIMEN ORIENTATION  
Horizontal: ± 8°
Vertical: ± 8°
SECTION THICKNESS SETTINGS  
Range: 0.25 - 50 µm
Setting Values: 0.25 - 0.5 µm (in 0.25 µm increments)
  0.5 - 5 µm (in 0.5 µm increments)
  5 - 20 µm (in 1 µm increments)
  20 - 50 µm (in 5 µm increments)
TRIMMING SECTION THICKNESS SETTINGS:  
Range: 1 - 300 µm
Setting Values: 1 - 10 µm (in 1 µm increments)
  10 - 20 µm (in 2 µm increments)
  20 - 50 µm (in 5 µm increments)
  50 - 100 µm (in 10 µm increments)
  100 - 300 µm (in 50 µm increments)

ADDITIONAL SPECIFICATIONS

Handwheel Balance System:
Handwheel Lock / Brake: 2 Mechanical Locks, 1 Electronic Brake
Safety Hand Wheel: Handle can be Centered
WASTE TRAY  
Type Standard Waste Tray
Waste Tray Volume 1400 ml
SELECTABLE CUTTING MODES  
Rock Mode: - with activated retraction
Single Mode:
Continuous Mode:
Step Mode:
Program Mode:
BLADE HOLDER  
Type: Semi-Thin Sectioning - Knife Holder GD

Resin Sectioning - Knife Holder NZ or Knife Holder E-TC

Paraffin Sectioning: 2-in-1 Blade Holder E
North-South Movement: ± 24 mm
East-West Movement: 3 Positions
Lateral Displacement Function: via knife holder
CE
 clamping top
SPECIAL FEATURES  
Remaining Feed Indicator Visual and Acoustical
Section Counter
Section Thickness Totalizer
Memory Position
Special Spindle for Precise Semi-Thin Sectioning
Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning
Precise 3D Object Head Stop Position

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Currently viewing
Type Mechanical Semi-Motorized Motorized Motorized
Precision-Orientation System
Force Balance System
2-in-1 Blade Holder
Specimen Cooling Option with RM CoolClamp
Standard Waste Tray
Silent Retraction
Personalized Coarse Feed Wheel
Fast Homing
Memory Position
Electronic Brake
Special Spindle for Precise Semi-Thin Sectioning
Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning
Precise 3D Object Head Stop Position

Downloads

Leica Biosystems file download

Configuration Guide

Leica Biosystems product brochure download

Brochure

Leica Biosystems Instructions for Use file download

IFU and SDS

IFU and SDS
Leica Biosystems download

Case Studies & White Papers

Leica Biosystems certificate download

Certificate

Configurations

Basic Instrument (14052458261)

  • Rotary microtome with Automated and Manual Modes
  • Automatic Electronic Brake
  • Special Spindle and expanded slow speed adjustment capabilities allows accurate specimen feeding for semi-thin sections of 250 nm
  • Precise 3D object head stop position allows for taking pictures of the cut specimen surface after each section to enable 3D reconstruction
  • Includes standard waste tray and top tray

HistoCore NANOCUT R Parts/Accessories

HistoCore NANOCUT R Publications