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HistoCore MULTICUT - Semi-Automated Rotary Microtome

149MULTI0C1, 14051856372

Manual Microtomy with a Twist of Motorization

When you need the precision and speed of manual sectioning with the efficiency benefits of a semi-automated setup, the HistoCore MULTICUT saves the day. The new generation of microtomes from Leica Biosystems is built upon our 145+ year heritage of market-leading microtome design. Combining the speed of a manual microtome with the precision of motorized specimen feeding, MULTICUT helps you get consistent, reproducible sections.

  • Advance or retract the specimen in the position most comfortable for you- manually using the Personalized Coarse Feed Wheel or user-motorized with the push of a button.
  • Enable fast and effortless trimming: with Fast Homing and Memory Position, the instrument can remember the optimal specimen position for your sectioning.
  • Produce high quality sections for IHC when using MULTICUT with the RM CoolClamp.
Contact us to get a quote. Call 88 6002 4929 to speak with a representative.

Product Features

Freedom of Choice and Effortless Trimming

Advance or retract the specimen in the position most comfortable for you - using the manual coarse feed wheel or the push of a button. In addition, the HistoCore MULTICUT can remember the optimal specimen position for your sectioning, enabling you to achieve fast and effortless trimming.

Freedom of Choice and Effortless Trimming

Antistatic Waste Tray (Brush Included)

With the Antistatic Waste Tray, MULTICUT helps you keep your workplace clean, efficient, and debris-free. The tray is made from antistatic material which prevents paraffin waste from sticking to the walls. It provides unmatched efficiency by reducing your cleaning time from minutes to seconds.

Antistatic Waste Tray (Brush Included)

Put (Almost) Anything on Top of your Microtome!

Our new models feature 40% more surface area on top of the microtome (23.5cm W x 27.5cm L, vs. 21.7cm W x 21.2cm L on the RM22xx series) so you can store the tools you need for your job – brushes, blades, wipes, and more.

40% more Surface Area on Microtome Top Compared to older RM22xx Series

Precision-Orientation System

Always get back to a 0-position home on the microtome, regardless of how you (or another tech) have changed the instrument's orientation.

Force Balance System

Minimize the risk of injury to the operator or specimen by an unbalanced object head.

Product Specifications


Type: Semi-Motorized
Nominal Supply Voltage: 100 / 120 / 230 / 240 V AC
Nominal Frequency: 50/60 Hz
Maximum Power Consumption: 40 VA
Protection Class: I
Power Fuses: 2 x T1.0 AL, 250V
Pollution Degree: 2
Overvoltage Category: II
Maximum Heat Emission: 70 J/s
Operating Temperature Range: +18°C to +30°C
Temperature Range During Storage: +5°C to +50°C
Relative Humidity During Operation: 20% to Max. 80% Non-Condensing
Relative Humidity During Storage: 10% to Max. 85% Non-Condensing

Dimensions & Weight

Width (including handwheel and coarse feed wheel): 477 mm
Depth (including waste tray): 620 mm
Height (without top tray): 295 mm
Weight (without accessories): Approx. 31 kg
Type: Separate control panel & in-housing integrated instrument control panel
Width: 94 mm
Depth: 193 mm
Height: 50 mm
Height (in inclined position): 81 mm
Weight (net): 0.5 kg

Microtome Performance Specs

Specimen Feed: approx. 24 mm ±1 mm
Vertical Stroke: 70 mm ±1 mm
Large Standard Clamp: 55 x 50 x 30 mm
Super Cassette Clamp: 68 x 48 x 15 mm
Motorized Sectioning Speeds: N/A
In Manual Sectioning Mode: 5 - 100 µm (in 5 µm increments); can be turned off
In Motorized Sectioning Mode: N/A
Horizontal: ± 8°
Vertical: ± 8°
Range: 0.5 - 100 µm
Setting Values: 0.5 - 5 µm (in 0.5 µm increments)
5 - 20 µm (in 1 µm increments)
20 - 60 µm (in 5 µm increments)
60 - 100 µm (in 10 µm increments)
Range: 1 - 600 µm
Setting Values: 1 - 10 µm (in 1 µm increments)
10 - 20 µm (in 2 µm increments)
20 - 50 µm (in 5 µm increments)
50 - 100 µm (in 10 µm increments)
100 - 600 µm (in 50 µm increments)

Additional Specifications

Handwheel Balance System:  
Handwheel Lock / Brake: 2 Mechanical Locks
Safety Hand Wheel: N/A
Coarse Feed Wheel Turn Direction: User-Selectable - Clockwise or Counter-Clockwise
Type Anti-static
Waste Tray Volume 1400 ml
Rock Mode:   - with activated retraction
Single Mode:  
Continuous Mode:  
Step Mode:  
Program Mode:  
Type: 2-in 1 for high and low profile blades
North-South Movement: ± 24 mm
East-West Movement: 3 Positions
Lateral Displacement Function: via knife holder CE clamping top
Remaining Feed Indicator Visual and Acoustical
Section Counter  
Section Thickness Totalizer  
Memory Position  
Special Spindle for Precise Semi-Thin Sectioning  
Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning  
Precise 3D Object Head Stop Position  

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Type Mechanical Semi-Motorized Motorized
Precision-Orientation System      
Force Balance System      
2-in-1 Blade Holder      
Specimen Cooling Option with RM CoolClamp      
Antistatic Waste Tray      
Silent Retraction      
Personalized Coarse Feed Wheel      
Fast Homing      
Memory Position      
Electronic Brake      






Frequently Asked Questions

HistoCore Microtomes
Does the new HistoCore RM antistatic tray fit on the older RM22xx series?

No – the microtome base plates of both series have different dimensions and are not compatible with each other.

How does the new antistatic waste tray reduce contamination?

The antistatic waste tray is made from resistant antistatic material to avoid debris sticking to the walls of the tray.

Is the new 2-in-1 blade holder compatible as a whole assembly with the older RM22xx series?

Yes – only in the combination blade holder and 2-in-1 blade holder.

Can we still use the backlighting with the new blade holder base for the 2-in-1 blade holder?

No – the 2-in-1 blade holder base does not have the cut-out for the backlighting.

Which accessories of the older RM22xx Series cannot be used with the HistoCore RMs anymore?
  1. Small section waste tray
  2. Large section waste tray
  3. Top tray – HistoCore RM top tray is 40% larger than the RM22xx series tray
  4. Cooling Device – too small to be placed on instrument top. However, it’s still good to place next to the instrument
What is the advantage of the personalized coarse feed wheel?

Convenience and ease-of-user – users can select their personal preference of coarse feed wheel turn direction. This feature is preserved from the RM22xx series, allowing users to trim at the high pace.

What is the advantage of “Fast homing”?

The return speed of the object head from front to home position has been reduced from 26 seconds (older series) to 13 seconds (new series). This accelerated speed helps to shorten the sectioning process each time the object head is returned to home position.

What is the advantage of the Memory Position?

When batch trimming and using the same height of blocks, Memory Position will help to accelerate the sectioning.

  1. First insert a new block
  2. Bring the block to the blade
  3. Set the Memo position (stored)
  4. Trim
  5. Remove block for re-cooling
  6. Press “Memo” – the object head returns to the set object change position
  7. Insert a new block – check position
  8. Trim again


Configuration 1 (149MULTI0C1)

  • Semi-automated rotary microtome
  • Includes Antistatic Section Waste Tray
  • Top Tray
  • Precision orientation with quick clamping system for specimen clamps
  • Universal cassette clamp
  • Two-in-one blade holder E for high and low-profile blades with lateral displacement function (includes blade holder base)

Basic Instrument (14051856372)

  • Semi-automated rotary microtome
  • Antistatic waste tray, top tray without specimen orientation or additional accessories
  • Completely customizable with a wide selection of accessories

HistoCore MULTICUT Parts/Accessories