Leica CM1950 - The Cryostat for Laboratories with Numerous Specimens and Varying Specimen Types
Overview
Depending on your specific requirements, the Leica CM1950 cryostat can be ordered with a variety of options. Start with the standard instrument and choose from a range of options to meet your laboratory's individual needs.
For an efficient workflow, all instruments come with a spacious cryocabinet to facilitate handling of multiple specimens. The cryostat provides sufficient space to organize your tools, freezing media and glass slides.
For In Vitro Diagnostic Use.
Features
Efficiency
A large freezing stage with numbered positions, additional tool trays, and a spacious, easy accessible storage area on top of the instrument help you to stay organized and focus on your sectioning job.
An optional vacuum system in combination with an anti-roll guide assists the user with section flattening.
Additionally, the Leica CM1950 cryostat can be ordered with a motor drive for fast and efficient sectioning of large numbers of specimen.
Quality
The CE blade holder for high- and low-profile disposable blades provides for a large clamping surface and supports reproducible section quality.
The CryoZone system creates a zone of uniformly cool air around specimen and blade.
Bright and glare-free LED illumination helps you clearly seeing the specimen during sectioning.
Specifications
Fast: 900 μm/s
Downloads
Parts & Accessories
View all Leica CM1950 Parts/AccessoriesKnowledge Hub
From tissue processing to Digital Pathology, our solutions empower labs with efficiency, precision, and reliability.
Neuroscience researchers usually need to see slices of whole brain in order to determine the location in brain of detail they are viewing under the microscope.
This article describes a system for embedding of tissues for the preparation of frozen sections. The system is easy to learn and offers many advantages over conventional methods, including speed, high precision and predictability, and reduced tissue wastage.
- The CryoZone™ system ensures that uniformly cold air flows continuously over critical areas of the cryochamber.
- Cold air flows directly from the evaporator onto the blade/ knife holder ensuring that the set temperature is maintained.
- The CryoZone™ system maintains a uniform temperature of the knife/blade holder and anti-roll guide, which improves section quality (stretching and less curling).
- No, it is not possible to retrofit a second compressor or motor drive.
- The desired instrument configuration must be specified when ordered.
- The HEPA filter must be exchanged every 3 months.
- There is no visible indicator on the instrument alerting the user to exchange the filter.
- To ensure the optimum cutting environment it is recommended to cool the CM1950 at least 5 hours from ambient to -25 °C or 8 hours from ambient to -35 °C prior to use.
- It is important that all accessories are pre-cooled before use (blade or knife holder, cutting tools, brushes etc.).
- After turning on the cryostat, the compressor for the cabinet cooling will cool the cabinet down to -5 °C before the second compressor, for object cooling, can be activated.
- Activation of object cooling is delayed to ensure that the object head does not cool faster, due to its smaller mass, compared to the rest of the cryostat. This prevents humidity in the chamber from causing frost build up on the object head, which could result in problems clamping the specimen disc.
- A Peltier element (electrical cooling) always has two sides – a cold and a warm side.
- The cold side is used to quickly freeze the specimens.
- The heat produced on the warm side has to be dissipated.
- The longer the Peltier element is activated, the more heat is produced and the warmer the cold side gets.
- To avoid “weakening” the freezing rate by a warming Peltier element, it is automatically switched off after 10 minutes of use.