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Geoffrey Rolls

Geoffrey Rolls

BAppSc, FAIMS

Geoffrey Rolls is a Histology Consultant with decades of experience in the field. He is a former Senior Lecturer in histopathology in the Department of Laboratory Medicine, RMIT University in Melbourne, Australia.

Published Pieces by Geoffrey Rolls

Download this publication to learn more about the various artifacts which may be encountered in histopathology. 

“组织处理”描述了将动物或人体组织从固定转换到使用合适的组织学专用蜡完全浸润、且包埋后准备好可以在切片机上进行切片的状态所需的步骤。

For routine diagnosis, the use of Hematoxylin and Eosin (H&E) is by far preferred for viewing cellular and tissue structure detail by pathologists. 

Immunohistochemistry (IHC) is used in histology to detect the presence of specific protein markers that can assist with accurate tumor classification and diagnosis. This article provides an overview and the basic steps used to create an optimal IHC stain.

Fixation is a critical step in the preparation of histological sections. If it is not carried out under optimal conditions or if fixation is delayed, a tissue specimen can be irreversibly damaged. No matter how much care is subsequently taken in tissue...

本指南将提供更多更好的ISH染色技巧。每一步都提供了有价值的实用性建议,以便在出现不可接受的结果时排除故障。

Get tips for better microtomy, flotation & section drying in this guide. Each step provides a valuable reminder of good histology practice and also helps with troubleshooting when unacceptable results do occur.

Get tips for better grossing in this guide. Each step provides a valuable reminder of good histology practice and also helps with troubleshooting when unacceptable results do occur.

Get tips for better specimen collection and transport in this guide. Each step provides a valuable reminder of good histology practice and also helps with troubleshooting when unacceptable results do occur.

A discussion on the techniques used for removing mineral from bone, or other calcified tissue, so that high-quality paraffin sections can be prepared.