Graham Taylor is a senior lecturer in viral and cancer immunology at the University of Birmingham, UK. His research group studies the immunology of Epstein-Barr virus (EBV), a common human herpesvirus infection linked to multiple diseases including 2% of cancers worldwide. His group have started to apply high dimensional analytical techniques to studies the virology and immunology of EBV diseases. These include mass cytometry to characterise immune cells in the blood, high-plex cytokine analysis of plasma and, most recently, high-plex immunohistochemistry to study tissue samples.
During the SARS-CoV2 pandemic Graham's research group, in collaboration with Prof. Paul Murray's group at the University of Limerick, have studied different virus-related diseases. These include: i) Multisystem inflammatory Syndrome of Children (MIS-C, also known as PIMS-TS) that develops in few children infected by the virus, and ii) COVID-19. For the latter his group have deployed a wide range of complementary techniques on post-mortem tissue samples.
COVID-19 is a complex multiphase disease in which the immune system causes disease exacerbation in some patients. This talk covers how digital pathology and tissue multiplexing techniques can be combined to effectively investigate the pathophysiology of SARS-CoV-2 to better inform the optimal selection and scheduling of therapeutic approaches.
COVID-19 is a complex multiphase disease in which the immune system causes disease exacerbation in some patients. This talk covers how digital pathology and tissue multiplexing techniques can be combined to effectively investigate the pathophysiology of SARS-CoV-2 to better inform the optimal selection and scheduling of therapeutic approaches.
