Lamp Fluorescent tube Lumilux Interna

Multiplexing is an important tool for simultaneous detection of multiple markers within a single tissue section. These educational infographics highlight the 5 key reasons to multiplex, as well as the main considerations for choosing chromogenic or immunofluorescent detection.

Delivering Excellence in IHC, ISH and Fluorescent Tissue-Based Research including Multiplex Whole Slide Scanning The Aperio VERSA is a comprehensive digital pathology scanner, designed and developed to support the diverse imaging needs of cutting edge research facilities. The combination scanner is optimized for precision scanning of brightfield and fluorescent samples, with the accuracy and resolution required for FISH . From tissue-based and proteomic markers, to subcellular, molecular and in-situ hybridization probes, the Aperio VERSA delivers high-resolution, reliable imaging. Users can create a permanent record of their research – even faint fluorescent samples, which are often subject to fading. The Aperio VERSA is ideal for scanning multiplex slides at any magnifica...

DAPI Counterstain is used as a counterstain for chromosomes. The counterstain consists of DAPI and antifade, which helps preserving the fluorescence signal. DAPI binds strongly to DNA, particularly to AT rich regions. It is used in the staining step of fluorescence in situ hybridization (FISH) on interphase nuclei and metaphase chromosomes.Counterstain Diluent is an antifade solution, which helps preserving the fluorescence signal. It can be used...

DAPI Counterstain is used as a counterstain for chromosomes. The counterstain consists of DAPI and antifade, which helps preserving the fluorescence signal. DAPI binds strongly to DNA, particularly to AT rich regions. It is used in the staining step of fluorescence in situ hybridization (FISH) on interphase nuclei and metaphase chromosomes. Counterstain Diluent is an antifade solution, which helps preserving the fluorescence signal. It can be use...

This programmable system automates the denaturation and hybridization steps in slide-based FISH procedures, and provides walk-away convenience for technical personnel. The low cost unit accepts a wide range of sample types, is easy to use, and reduces hands-on time while ensuring overall precision and accuracy in FISH assays.

San Diego, CA – November 8, 2022. Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging, has acquired Cell IDx, Inc., a leader in multiplexed tissue profiling. Founded in 2012 and headquartered in San Diego, California, Cell IDx provides multiplex staining panels, tissue staining, and imaging and analysis services. Cell IDx’s UltraPlex technology allows simultaneous detection of multiple biomarkers in many immunoassays through fluorescent and chromogenic multiplex immunohistochemistry (“IHC”) staining technology, and automated chromogenic detection of multiple markers on Leica Biosystems’ BOND RX fully automated research stainer. Together, UltraPlex and BOND RX with high throughput imaging allows researchers to detect three or more ...

Fluorescent in situ hybridization (FISH) identifies or labels target genomic sequences so that their location can be studied. DNA sequences from appropriate chromosome specific probes are first labeled with reporter molecules. The labeled DNA probe is then hybridized to the metaphase chromosomes or interphase nuclei on a slide. After washing, the specimen is screened for the reporter molecules by fluorescence microscopy.For use on metaphase and i...