Learn more about tissue processing artifacts, what is "optimal" and what is "not," and how to optimize tissue processing techniques with a downloadable checklist for success.

Slide 1 Welcome Slide 2 Slide 3 Discuss Pre-Analytics and the impact of improper fixation and artifacts on tissue processing Discuss Fixation and the impact of incomplete fixation on tissue processing Describe the impact of improper Prosection Determine satisfactory Processing of samples Explain why routine Maintenance is a critical success factor to proper tissue processing Slide 4 This slide has two examples of what the ideal sections in a perfect world look like under the scope. The skin section on the left is clean looking with the Eosin staining the components of the dermis with different shades. The colon section on the right is crisp with well-defined nuclei and cilia. There is no background staining or muddiness to the stain. Slide 5 One artifact seen the lab that is n...

Following our two-part webinar series of Tips & Tricks to Better Histology, further questions were raised by customers referring to specific issues encountered during histology/staining practice. Some of these questions are answered here to help combat issues experienced in the laboratory. 

Following our 2-part webinar series of Tips & Tricks to Better Histology, questions about histology-related issues were received from customers and answered by Leica Biosystems. Here, in Histology Tips & Tricks: Questions and Answers, Part 2, more questions are answered, specifically regarding decalcifying agents, and tissue section bubbling/cracking.

Get tips for better microtomy, flotation & section drying in this guide. Each step provides a valuable reminder of good histology practice and also helps with troubleshooting when unacceptable results do occur.

In this webinar, Fiona Tarbet will investigate some of the effects of poor technique on section and stain quality and identify ways of producing better results.

Fluorescent in situ hybridization (FISH) identifies or labels target genomic sequences so that their location can be studied. DNA sequences from appropriate chromosome specific probes are first labeled with reporter molecules. The labeled DNA probe is then hybridized to the metaphase chromosomes or interphase nuclei on a slide. After washing, the specimen is screened for the reporter molecules by fluorescence microscopy.For use on metaphase and i...