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Geoffrey Rolls, BAppSc, FAIMS
Cindy Sampias, JD CT(ASCP)HTL
For routine diagnosis, the use of Hematoxylin and Eosin (H&E) is by far preferred for viewing cellular and tissue structure detail by pathologists. We continue to use this simple and essential stain today, which has remained unchanged for well over a century.
Cindy Sampias, JD CT(ASCP)HTL
Though the H&E stain is a relatively simple stain to perform, there are a variety of artifacts that can interfere with a good stain. Artifacts can be attributed to a variety of causes.
Cindy Sampias, JD CT(ASCP)HTL
If you are considering purchasing a new clinical microscope, you will think about many options, vendors, and microscope models. Here are some top tips to help you come to the best buying decision.
After a joint has been decalcified, the loss of proteoglycans in the articular cartilage causes it to fold and ripple during the staining process. When this occurs, it makes it impossible to perform histo-morphometry or measurements of the cartilage.
Carolyn Doan, HT (ASCP)
Microorganisms are living organisms which include bacteria, fungi, protozoa and viruses. Bacteria, fungi and protozoa can be identified and classified with histochemical procedures and viruses are generally identified with immunohistochemical procedures.
Carolyn Doan, HT (ASCP)
"Special stain" is a term used to refer to many alternative staining techniques that are used when the traditional H&E does not provide all the information the pathologist or researcher needs from a tissue slide.
Carolyn Doan, HT (ASCP)
“Special stain” is a term used to refer to many alternative staining techniques that are used when the traditional H&E does not provide all the information the pathologist or researcher needs from a tissue slide.
Steven Westra, Reagent Product Specialist, Leica Biosystems
Muscular Dystrophy is a genetic disease characterized by progressive weakness and degeneration of the skeletal muscles which controls movement. The muscles of the heart and some other involuntary muscles are also affected in some forms of muscular dystrophy.
Geoffrey Rolls, BAppSc, FAIMS
Fixation is a critical step in the preparation of histological sections. If it is not carried out under optimal conditions or if fixation is delayed, a tissue specimen can be irreversibly damaged.
James Anderson, Global Marketing Manager
The accurate and repeatable detection of a specific protein is central to successful IHC staining. Primary antibodies bind to a small region or multiple regions (epitope/s) of these very complex proteins.