8 result(s) for 'Tissue Preparation'
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Fluorescent in situ hybridization (FISH) identifies or labels target genomic sequences so that their location can be studied. DNA sequences from appropriate chromosome specific probes are first labeled with reporter molecules. The labeled DNA probe is then hybridized to the metaphase chromosomes or interphase nuclei on a slide. After washing, the specimen is screened for the reporter molecules by fluorescence microscopy.For use on metaphase and i...
Novocastra Epitope Retrieval Solutions are intended for Heat Induced Epitope Retrieval (HIER) on formalin-fixed, paraffin-embedded tissue sections as part of an immunohistochemical procedure.
HIER using an appropriate pH solution improves the staining of some antibodies by exposing epitopes within tissue that have been masked during fixation.  A universal HIER technique suitable for all
epitopes does not exist. A combination of different hea...
The BOND-PRIME ARC Refresh Kit assists in maintaining the Active Reagent Control (ARC) Modules, the precisely engineered, individual staining chambers to run any staining protocol at any time. They provide consistent and reproducible staining with highly-controlled dispense, reagent flow, and precise incubation to each and every slide.The ARC kit comes with 24 ARC Covertiles and a mixing station. The semi-permanent, self-cleaning ARC Covertile pr...
BOND ancillaries have been designed for Leica Biosystems fully-automated BOND systems: BOND-MAX and BOND-III systems. Used in the development and validation of BOND ready-to-use primary
antibodies and ISH probes - choose Leica Biosystems reagents for the assurance of a quality result in your laboratory. BOND Wash Solution 10X Concentrate is a concentrated buffer solution, requiring initial
dilution. The diluted solution is for washing sections of...
Antigen Background
Postmeiotic segregation increased 2 (PMS2), also known as PMS1 protein homologue 2, is a DNA mismatch repair (MMR) protein. The PMS2 gene family members are found in clusters on chromosome 7. PMS2 is a 96 kDa mismatch repair protein closely related to MLH1, MLH3 and PMS1, which are homologs of the bacterial mutL gene. The PMS2 protein forms a heterodimer with the MLH1 protein which is then activated in the presence of ATP; this...
“Novolink Polymer Detection Systems are used for the visualization of mouse IgG, mouse IgM and rabbit IgG primary antibodies. Novolink Polymer contains component reagents of these systems. The
Novolink Polymer Detection Systems utilize a novel controlled polymerization technology to prepare polymeric HRP-linker antibody conjugates. Therefore, the problem of non-specific staining that can occur with Streptavidin/Biotin detection systems due
to end...
Flexible Image Analysis Platform for Every Cytogenomics Laboratory
The CytoInsight GSL automated image analysis and case management system is a comprehensive Cytogenomics solution that improves quality and turnaround time from acquisition to analysis while reducing hands-on time at every step in your process.
The CytoInsight GSL system improves image processing, provides system flexibility, and offers increased cybersecurity to deliver the tools to build your system to fit your Cytogenomics lab workflow.
From prepared slide to report and back, the CytoInsight GSL flexible platform for brightfield and fluorescence image analysis provides unlimited scanning for a walk-away solution to meet the evolving needs of your Cytogenomics laboratory.
Find Breakthroughs Faster with the Freedom to Discover
Speed up your next big discovery. Use the BOND RX to confidently complete IHC, ISH, FISH, CTC, multiplexing and other tests. Explore your ideas in a variety of ways via open reagents, open detection kits, and customizable protocols. The BOND RX provides an easy way for labs to fully automate tests and accelerate research programs.
Accelerate test programs through speed, efficiency, and consistent automation, reducing manual work so that researchers can spend less time at the bench and more time innovating.
Preserve morphology and integrity of precious tissue with the unique Covertile system that allows you to dispense reagents in a highly-controlled and more consistent manner. 91% of...