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Leica CM3050 S Cryostat

Processing multiple specimen and performing serial cuts can result in high section numbers. Nevertheless, reproducibility can't be compromised. Permanent attention to detail and many hours in front of the cryostat can be exhausting for the user. The Leica CM3050 S cryostat is designed to help with exactly these time-consuming jobs.

The low working height and available knee space of the Leica CM3050 S cryostat allow the user to work comfortably while sitting. Motorized drive and section counter improve productivity for multiple serial sections.

Particularly when working with delicate specimens, e.g. brain samples, the precise specimen orientation and the specimen feed system provide for reproducible sections.

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For In Vitro Diagnostic Use

Technical Specifications


Width: 882 mm
Depth: 766 mm
Height: 1040 mm
Weight (incl. microtome): approx. 180 kg
Temperature setting range: 0°C to -40°C
Maximum specimen size: 40 x 55 mm
Cutting speed: 0.1 mm/s to 170 mm/s
0.1 mm/s to 100 mm/s
Vmax: 210 mm/s
Section thickness setting 0.5 to 300 μm
Maximum specimen size 40 mm x 55 mm
Horizontal specimen feed 25 mm
Vertical specimen stroke 59 mm
Specimen retraction 50 pm
Specimen precision orientation by 8° (x/y/z axis)
Trimming 5 to 150 μm ± 0,5 μm in steps of 5, 10, 30, 50, 100 and 150 μm
Motorized coarse feed at two speeds 500 μm/s and 1,000 μm/s
Cutting speed ranges 0.1 mm/s to 170 mm/s, 0.1 mm/s to 100 mm/s, Vmax 210 mm/s
Temperature setting range 0°C to -40°C
Defrosting programmable 1 automatic defrost cycle/24 h duration; from 6 to 12 min; manual defrosting
Freezing shelf temperature Approx. -43°C at an ambient temperature of 22°C
Temperature setting range -10°C to -50°C (+/-3 K)
Dimensions (W x H x D) 882 x 1040 x 766 mm
Weight (including microtome) Approx. 180 kg
Power draw 1800 VA

Product Features

Precision Sectioning

When working with large samples, accurate specimen orientation and feed are crucial. The precise specimen orientation system with zero position provides for x/y adjustment of up to 8°. The specimen feed system with 25mm horizontal feed allows for reproducible thin sections.

Precision Sectioning

Precision Cooling

An independent refrigeration system for the object head provides for temperature changes and efficient specimen temperature control to adjust for difficult samples such as brain or fatty tissue.

Highly efficient insulating materials and a dedicated cooling system support stable cryochamber temperatures, even when producing serial sections all day long.

Precision Cooling

Stay Organized

With critical items at hand, you can focus on your sectioning job. Freezing stage and tool tray in a large cryochamber, as well as an easily accessible storage area on top of the cryostat help you to stay organized. The motor drive with foot-pedal enables you to have both hands free for sample handling.

Stay Organized

Stay Focused

Section thickness totalizer and counter with reset button facilitate target preparation and promote fast trimming between levels. With the reverse section counter, a preselected number of sections can be carried out in both sectioning and trimming mode.

Stay Focused

Comfortable Sitting Position

The Leica CM3050 S cryostat with its low working height and available knee space allows the user to work comfortably while sitting.

The optional electrohydraulic height adjustment grants tall users an adjustable working height and even more knee space. For users who prefer standing when sectioning, the height adjustment can lift the instrument up to standing working height.

Comfortable Sitting Position




Leica CM3050 S Parts/Accessories