10 result(s) for 'Fluorescent'
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DAPI Counterstain is used as a counterstain for chromosomes. The counterstain consists of DAPI and antifade, which helps preserving the fluorescence signal. DAPI binds strongly to DNA, particularly to AT rich regions. It is used in the staining step of fluorescence in situ hybridization (FISH) on interphase nuclei and metaphase chromosomes.Counterstain Diluent is an antifade solution, which helps preserving the fluorescence signal. It can be used...
DAPI Counterstain is used as a counterstain for chromosomes. The counterstain consists of DAPI and antifade, which helps preserving the fluorescence signal. DAPI binds strongly to DNA, particularly to AT rich regions. It is used in the staining step of fluorescence in situ hybridization (FISH) on interphase nuclei and metaphase chromosomes. Counterstain Diluent is an antifade solution, which helps preserving the fluorescence signal. It can be use...
This programmable system automates the denaturation and hybridization steps in slide-based FISH procedures, and provides walk-away convenience for technical personnel.
The low cost unit accepts a wide range of sample types, is easy to use, and reduces hands-on time while ensuring overall precision and accuracy in FISH assays.
The Leica HER2 FISH System for BOND combines PathVysion®* LSI® HER2/CEP17® FISH probes (supplied by Abbott Molecular Inc.) and advanced BOND automation.
Now laboratories, pathologists, and ultimately patients can benefit from easy and accurate FISH assessment of HER2 gene status in breast cancer tissue.
Easy - eliminate manual complexity and increase standardization through automation
Efficient - create a Lean workflow with single or batched cases
Accurate – deliver accurate results for high diagnostic confidence
The Bond Oracle HER2 IHC System is a fully-automated assay to accurately determine HER2 oncoprotein status in breast and gastric cancer tissue as an aid in the assessment of patients for whom Herceptin® (trastuzumab) treatment is being considered.
Accurate - optimized to precisely separate 1+ and 2+ cases gives you excellent FISH concordance, reducing avoidable FISH requests.
Drive Consistency - standardized protocols for uniform staining, decreased process variation, and consistent results.
Maximize Efficiency - full automation frees up your skilled staff for other high-value tasks.
A Complete Solution - integrated ready-to-use reagents, control slides, and advanced automation ensure quality and consistency.
Fluorescent in situ hybridization (FISH) identifies or labels target genomic sequences so that their location can be studied. DNA sequences from appropriate chromosome specific probes are first labeled with reporter molecules. The labeled DNA probe is then hybridized to the metaphase chromosomes or interphase nuclei on a slide. After washing, the specimen is screened for the reporter molecules by fluorescence microscopy.For use on metaphase and i...
Flexible Image Analysis Platform for Every Cytogenomics Laboratory
The CytoInsight GSL automated image analysis and case management system is a comprehensive Cytogenomics solution that improves quality and turnaround time from acquisition to analysis while reducing hands-on time at every step in your process.
The CytoInsight GSL system improves image processing, provides system flexibility, and offers increased cybersecurity to deliver the tools to build your system to fit your Cytogenomics lab workflow.
From prepared slide to report and back, the CytoInsight GSL flexible platform for brightfield and fluorescence image analysis provides unlimited scanning for a walk-away solution to meet the evolving needs of your Cytogenomics laboratory.
The t(12;21), a cryptic translocation rarely observed by conventional cytogenetics, was first identified by fluorescence in situ hybridization (FISH). In ALL blasts, this translocation fuses the 5' part of the ETV6 (previously known as TEL) gene with almost the entire RUNX1 (previously known as AML) (CBFA2) gene, producing the chimeric transcript ETV6-CBFA2. The t(12;21) (p13;q22) has also been identified as the most frequent chromosomal abnormal...
Well-differentiated liposarcoma/atypical lipomatous tumor and dedifferentiated liposarcoma are among the most common malignant soft tissue tumors presented in older adults. These tumors can be difficult to distinguish from benign lipomatous neoplasms and other high-grade sarcomas. Amplification of the MDM2 gene has been identified in lipomatous neoplasms. The use of fluorescence in situ hybridization in identifying MDM2 amplification has made the...
Find Breakthroughs Faster with the Freedom to Discover
Speed up your next big discovery. Use the BOND RX to confidently complete IHC, ISH, FISH, CTC, multiplexing and other tests. Explore your ideas in a variety of ways via open reagents, open detection kits, and customizable protocols. The BOND RX provides an easy way for labs to fully automate tests and accelerate research programs.
Accelerate test programs through speed, efficiency, and consistent automation, reducing manual work so that researchers can spend less time at the bench and more time innovating.
Preserve morphology and integrity of precious tissue with the unique Covertile system that allows you to dispense reagents in a highly-controlled and more consistent manner. 91% of...