Immunohistochemistry (IHC) detects proteins of interest within whole tissue sections, keeping cellular organization intact.

Slide 1 Hello, hello; thank you so much for that introduction. Let's get started. Oh, I'm sorry, I just need to hit this next button here. So my name is Mark Lawson. Thank you for joining us in this webinar. I'm here to present BOND RX tips, tricks, and optimization. It's going to be a user guide from the BOND RX and chromogenic multiplexing in the research application. Slide 2 So, my name is Mark Lawson. I'm an application specialist on the Life Sciences team at Leica Biosystems I provide technical support for the Life Sciences portfolio, including but not limited to the BOND RX, the BOND RXm, and a wide array of reagents. So I've worked in the histology field for about 15 years and in both clinical and research spaces. I started off as a histotechnologist and worked my way up...

Multiplexing is an important tool for simultaneous detection of multiple markers within a single tissue section. These educational infographics highlight the 5 key reasons to multiplex, as well as the main considerations for choosing chromogenic or immunofluorescent detection.

Bond Polymer Refine HRP Plex Detection offers researchers the ability to completely tailor their approach to chromogenic multiplex staining. The base platform of peroxide block, post primary and HRP polymer can be combined with a bespoke combination of chromogens and your counterstain of choice. This detection system is essential for fully automated chromogenic multiplexing.ComponentsBOND Polymer Refine HRP Plex Detection (DS9914) consists of 3 c...

Leica biosystems BOND RX stainer can aid biomarker and drug discovery by offering fast, customized, consistent, fluorescent or chromogenic multiplex IHC and ISH on your research samples. The result? Freeing up your time to innovate, investigate and discover!

Learn more about multiplexing and explore these educational videos and infographics to understand how to choose chromogen colors for multiplex, as well as the different detection systems available for multiplex assays. 

San Diego, CA – November 8, 2022. Leica Biosystems, a technology leader in automated staining and brightfield and fluorescent imaging, has acquired Cell IDx, Inc., a leader in multiplexed tissue profiling. Founded in 2012 and headquartered in San Diego, California, Cell IDx provides multiplex staining panels, tissue staining, and imaging and analysis services. Cell IDx’s UltraPlex technology allows simultaneous detection of multiple biomarkers in many immunoassays through fluorescent and chromogenic multiplex immunohistochemistry (“IHC”) staining technology, and automated chromogenic detection of multiple markers on Leica Biosystems’ BOND RX fully automated research stainer. Together, UltraPlex and BOND RX with high throughput imaging allows researchers to detect three or more ...

The first virtual event of the year recaptured the conference atmosphere at the Multiplex User Meeting. With Leica Biosystems total multiplex solutions and trusted partners, advances in multiplex IHC were innovatively showcased to customers via live presentations, on-demand webinars, virtual exhibition hall, networking room and, virtual lab tour!

Imagine the possibilities for your Chromogenic Multiplex with Leica Biosystems and Cell IDx To accelerate the discovery journey in cancer research, Leica Biosystems has partnered with Cell IDx, a technology leader in multiplexed cellular immunodiagnostics, developing highly sensitive and specific reagents for research and clinical immunohistochemistry to meet the needs of precision medicine. Cell IDx technology allows the automated detection of multiple markers on the BOND RX staining system. The technology uses primary antibodies from any species, employing a single antigen retrieval step that allows detection of three chromogen stains in 4.5 hours and four chromogen stains in 6 hours. The process is simple, fast, and fully automated on the BOND RX platform and Aperio Brightfi...