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Antigen Backgroundp16 (INK4a) (Cyclin-dependent kinase inhibitor 2A (CDKN2A)) is a tumour suppressor protein associated with cell cycle progression, specifically in the regulation of transition from G1 phase of the cell cycle in to the S phase. Oncogenic mutations in the CDKN2A gene that encodes p16 (resulting in over or under expression of the protein) is associated with a wide range of cancers and cancer precursor lesions.Disclaimerp16 is recom...