7 result(s) for 'PDL1'
1 - 7 of 7 results for 'PDL1'
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Antigen BackgroundProgrammed death-ligand 1 (PD-L1), CD274 or B7 Homolog 1(B7-H1) is a protein encoded by the CD274 gene. When bound to its ligands, PD-1 and B7.1, it plays an immunosuppressive role by inhibiting T-cell activity. Overexpression of PD-L1 by cancer cells may enable them to evade the host immune response, conferring a growth advantage to such tumours. PD-L1 expression levels detected by immunohistochemistry can therefore be of progn...
Antigen BackgroundPD-1 (Programmed Death 1) is a 55KDa Type I transmembrane cell surface receptor which is expressed by T-cells during activation. It is also upregulated in B-cells, dendritic cells, natural killer cells and some myeloid cells, suggesting a broad role for PD1 in immune regulation. PD-1 interacts with at least two ligands: PD-L1 and PD-L2. PD-1/PD-L1 interaction is important in many Tcell functions including acute and chronic infla...
DESCRIPTION: Chromogenic multiplex IHC kit for BOND RX - human PD-L1, CD8, PanCK
SIZE: 10 slides
PRODUCT OVERVIEW: Kit for chromogenic multiplex IHC staining of 10 slides plus a single negative control slide on the BOND RX with V7.0 software.
1° Antibody
Clone
1° Tag
2° Antibody
Chromogen
PD-L1
73-10
UT014
Anti-UT014-HRP
Leica Blue
CD8
EPR10640(2)
UT015
Anti-UT015-AP
Leica Refine Red
PanCK
AE1/AE3
UT016
Anti-UT016-HRP
Yellow
Leica Ref...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD8, CD68, PD-1, PD-L1, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD8
EPR10640(2)
UT015
Anti-UT015
CL490
CD68
C68/684
UT019
Anti-UT019
CL750
PD-1
EPR4877
UT016
Anti-UT016
CL650...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD8, CD68, Pan-CK, PD-L1, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol.
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD8
EPR10640(2)
UT015
Anti-UT015
CL490
CD68
C68/684
UT019
Anti-UT019
CL750
Pan-CK
AE1/AE3
UT016
Anti-UT016
...
DESCRIPTION: Kit for fluorescent multiplex IHC staining of human CD68, CD163, Pan-CK, PD-L1, detection with 490, 550, 650, 750 nm fluors
SIZE: 5 slides
PRODUCT OVERVIEW: All components required to stain 5 multiplex slides plus a single negative control slide with simple two-step protocol.
1° Antibody
Clone
1° Tag
2° Antibody
2° Fluor
CD6
C68/684
UT019
Anti-UT019
CL750
CD163
EPR19518
UT015
Anti-UT015
CL490
Pan-CK
AE1/AE3
UT016
Anti-UT016
...
DESCRIPTION: Chromogenic multiplex IHC kit for BOND RX - human CD68, CD163, PD-L1
SIZE: 10 slides
PRODUCT OVERVIEW: Kit for chromogenic multiplex IHC staining of 10 slides plus a single negative control slide on the BOND RX with V7.0 software.
1° Antibody
Clone
1° Tag
2° Antibody
Chromogen
CD8
C68/684
UT021
Anti-UT021-AP
Leica Refine Red
CD163
EPR19518
UT015
Anti-UT015-HRP
Yellow
PD-L1
73-10
UT014
Anti-UT014-HRP
Leica Blue
Leica Refin...