2 result(s) for 'P63'
1 - 2 of 2 results for 'P63'
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Antigen Background
p63 is a type II integral membrane protein predominantly localized in the rough endoplasmic reticulum. p63 is reported to be expressed in a number of normal tissues including proliferating cells of the epithelium, cervix, urothelium and prostate. p63 is also reported to be expressed in most poorly differentiated squamous cell carcinomas.
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p63 Protein is recommended for the detection of specific antigens of interest in...
Antigen Backgroundp40 (Delta Np63) is a truncated product of the p63. It is normally expressed in the basal or progenitor cell layer of stratified epithelia, basal cells of prostate, as well as myoepithelial cells of breast and salivary glands, and cytotrophoblasts in placenta, and shows a nuclear staining pattern with IHC. Among the numerous neoplasms positive for p40, squamous cell carcinomas of pulmonary and non-pulmonary origin can be identif...