3 result(s) for 'Lung'
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Deletions of chromosome 13q14 have been reported not only in CLL but in a variety of human tumors, including other types of lymphoid and myeloid tumors, as well as prostate, head and neck, and non-small cell lung cancers. The deletion of 13q may be limited to a single locus (13q14), or accompanied with the loss of a larger interstitial region of the long arm of chromosome 13. A minimal critical region of 400 kb has been described containing the D...
Amplification of the 3q26-q27 has a high prevalence in cervical, prostate, lung, and squamous cell carcinoma. This amplification can also be found to a lesser extent in CLL patients. The minimal region of amplification was refined to a 1- to 2-Mb genomic segment containing several potential cancer genes including TERC, the human telomerase RNA gene. The TERC (3q26) specific FISH probe is optimized to detect copy numbers of the TERC (previously kn...
Deletions of chromosome 13q14 have been reported not only in CLL but in a variety of human tumors, including other types of lymphoid and myeloid tumors, as well as prostate, head and neck, and non-small cell lung cancers. The deletion of 13q may be limited to a single locus (13q14), or accompanied with the loss of a larger interstitial region of the long arm of chromosome 13. A minimal critical region of 400 kb has been described containing the D...