15 result(s) for 'Ki67'
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Antigen Background
The Ki67 antigen is a nuclear protein which is expressed in all active parts of the cell cycle (G1, S, G2 and mitosis) but is absent in resting cells (G0). In contrast to many other cell cycle-associated proteins, the Ki67 antigen is consistently absent in quiescent cells and is not detectable during DNA repair processes. Thus, the presence of Ki67 antigen is strictly associated with the cell cycle and confined to the nucleus, ...
Leica Microsystems continues to make high-quality IHC more efficient with the release of eight important new antibodies in the Bond ready-to-use (RTU) format.
New antibodies:
Beta-Catenin (clone 17C2)
Cytokeratin 17 (clone E3)
Gastrin (polyclonal)
Galectin-3 (clone 9C4)
Ki67 (clone K2)
MLH1 (Mismatch Repair Protein) (clone ES05)
Multiple Myeloma Oncogene 1 (MUM1) (clone EAU32)
Tartrate-Resistance Acid Phosphatase (clone 26E5)
Leica Microsystems has selected each new product for superior performance and clinical relevance. A highlight of this release is the new K2 clone for Ki67. This new clone has shown exceptional results during development and is now recommended as the preferred Ki67 clone (the older MM1 clone will continue to be available).
Another antibody of great inter...
Phenotyping Tumor Microenvironment Using DNA Barcoded Multiplex Technology Chifei Sun GSK IVIVTBIBCellular Biomarkers Collegeville, PA
I have no conflict of interests with Leica Biosystems, Ultivue and Indica Labs. – All the materials used in this presentation are for educational purpose only. – The human biological samples were sourced ethically, and their research use was in accord with the terms of the informed consents under an IRB/EC approved protocol. Statement 9/25/2020 2
Understand the complexity of tumor microenvironment and its importance in drug development – Introduce the Ultivue DNA barcoding and exchange technology for multiplex immunofluorescence – Highlight the processes of image fusion, spatial analysis and colocalization of markers on individual cells Learnin...
H&E is an important tool for disease research and drug development and is being increasingly combined with digital pathology technology. Image quality is important for slide digitization to ensure that interpretation is accurate. Take a look at some images here, produced by our digital pathology scanners.