2 result(s) for 'CD8'
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Antigen Background
The CD8 molecule is composed of two chains and has a molecular weight of 32 kD. It is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35% of human peripheral blood lymphocytes.The CD8 antigen is reported to be detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15-30% of bone marrow cells.
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Antigen Background
The CD57 glycoprotein, also known as HNK-1, has a molecular weight of 110 kD. It is found on a subset of mononuclear cells with natural killer activity and on neuroectodermal cells expressing myelin-associated glycoprotein. Many cells which co-express CD57 and CD8 proteins are a subset of suppressor/cytotoxic T cells. These cells play a role in the rejection of grafts in acute graft versus host disease. The CD57 molecule is not...