Aperio FISH Brk/Fus Algorithm Analyze

Aperio FISH Brk/Fus Algorithm – Automated FISH Break-apart & Fusion Analysis

Aperio Digital Pathology FISH Break-apart Fusion Image Analysis

The Aperio FISH Brk/Fus Algorithm enables highly-specific and sensitive detection of DNA sequence translocations (break-apart and fusion) in whole slide digital pathology images. It provides standardized results, removing the inter- and intra-user variability that is inherent in manual FISH counts. Aperio FISH Brk/Fus Algorithm has been developed for full interoperability with the Aperio digital pathology solutions for researchers.


For Research Use Only. Not for use in diagnostic procedures. For specific product indications and more information click here.

Aperio CS2 and Aperio AT Turbo are registered products under the ScanScope® name.

Copyright © 2016 Leica Biosystems Imaging, Inc. All Rights Reserved. LEICA and the Leica logo are registered trademarks of Leica Microsystems IR GmbH. Aperio is a registered trademark of Leica Biosystems Imaging, Inc. in the and other countries.

Saiba mais

Developed with you in mind

Aperio FISH Brk/Fus Algorithm is designed to evaluate break-apart and fusion events within target gene sequences. Specifically tailored to meet workflow challenges, such as the occurrence of “beads on a string” signals, you can be confident that the algorithm is ready to meet your needs.

Get the most from your samples

Analyze complex patterns of gene sequence translocation precisely and automatically. Up to 7 signals of interest, in addition to nuclear counterstain, can be analyzed on a single slide. Cells are classified into multiple user-defined categories based on number of signals, break-aparts, and fusions.

Easy to use

Set-up of the algorithm is performed via an intuitive tuning wizard, so even inexperienced users can quickly and easily create their own custom analysis tool. Visual mark-up is provided at each stage in the process, with live feedback on results as each setting is changed.

Flexible analysis

Customizable inputs allow the algorithm to be used flexibly with a variety of probes and applications. Users can exclude cells that are not of interest, and adjust signal detection to exclude staining artefacts, haze, and hot signals that may affect analysis.