2 result(s) for 'Histopathology'
1 - 2 of 2 results for 'Histopathology'
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Antigen Background
CD103, also known as alpha E integrin & human mucosal lymphocyte antigen 1, is an integrin protein with expression on intraepithelial T cells & some peripheral regulatory T cells. CD103 is expressed at high levels on tumour-infiltrating FOXP3-positive regulatory T cells in cancer and CD103-positive T cells are strongly associated with patient survival in high-grade serous ovarian cancer.
CD103 expression has been suggested as a...
Antigen Background
Bcl-6 is a proto-oncogene that encodes a Kruppel-type zinc-finger protein of 95 kD and shares homology with other transcription factors. Bcl-6 protein is mainly expressed in normal germinal center B cells and related lymphomas. It has been shown that the Bcl-6 proto-oncogene is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have also been detected in 33-45% of diffuse large B c...