Difficult Blocks and Reprocessing
What To Do When Your Block Won’t Section
From time to time, in all histopathology laboratories, paraffin blocks will be encountered that are difficult or even impossible to section. This book provides guidance on how to deal with these difficult blocks to get the best possible section, and how to identify and avoid a repeat of underlying causes.
Part 1: The initial assessment
Why is my block difficult or impossible to cut?
Part 2: Getting more information
Examples of typical problems and their causes
Part 3: Detailed Solutions
Detailed solutions for difficult blocks
Part 4: Root Causes
The root cause of processing problems and their prevention
Part 5: Validation
How to validate a reprocessing method
Part 6: Appendix
Reprocessing decision trees