Plasminogen Activator Inhibitor (Type 1) Novocastra
Plasminogen activator inhibitor (Type 1), PAI-1 is a 48 kD protein which inhibits the conversion of plasminogen to plasmin. It is the principal inhibitor of the plasminogen activators t-PA and u-PA. PAI-1 is structurally related to the serine protease inhibitor (serpin) superfamily. The serpins are known to undergo a conformational rearrangement upon cleavage of the reactive central peptide bond (P1-P1') and it is this conformational difference between the active and cleaved forms which determine their reactivity.PAI-1 is reported to be expressed by endothelial cells and is stored in platelets.
|PAI-1||1ml NCL-PAI-1||Lyophilised Concentrated Monoclonal Antibody||P||Info||MSDS||1|
|PAI-1-S||0.1ml NCL-PAI-1||Lyophilised Concentrated Monoclonal Antibody||P||Info||MSDS||1|
|PAI-1-U||1ml NCL-PAI-1 US IVD||Lyophilised Concentrated Monoclonal Antibody||P||Info||MSDS||1|