Wilms' Tumor
Primary Antibodies
Wilms' Tumor
Human Wilms tumor: immunohistochemical staining for WT1 using NCL-L-WT1-562. Note intense nuclear staining of malignant cells. Paraffin section.
Antigen Background
Wilms' tumor protein (WT1) has a role in transcriptional regulation and is expressed in the kidney and a subset of hematopoietic cells. Alteration of transcription factor function is a common mechanism in oncogenesis. The WT1 protein contains a DNA binding domain and any deletions or point mutations of the WT1 gene which destroy this activity result in the development of the childhood nephroblastoma Wilms' tumor and Denys-Drash syndrome. The description of WT1 involvement in nephroblastoma is not clear.
CLONE: WT49
Request a quote
| Code | Name | Configuration | Use | Datasheet | MSDS | Qty |
|---|---|---|---|---|---|---|
| PA0562-CN | 7mL Wilms Tumor Bond RTU Primary (China) | Bond ready to use reagent | P(HIER) | MSDS |
|
|
| PA0562 | 7ml Wilms Tumor Bond RTU Prim | Bond ready to use reagent | P(HIER) | Info | MSDS |
|
| WT1-562-L-S | 0.1ml NCL-L-WT1-562 | Liquid Concentrated Monoclonal Antibody | P(HIER) | Info | MSDS |
|
| WT1-562-L-CE | 1ml NCL-L-WT1-562 | Liquid Concentrated Monoclonal Antibody | P(HIER) | Info | MSDS |
|
| WT1-562-L | 1ml NCL-L-WT1-562 | Liquid Concentrated Monoclonal Antibody | P(HIER) | Info | MSDS |
|
| WT1-562-L-CE-S | 0.1ml NCL-L-WT1-562 | Liquid Concentrated Monoclonal Antibody | P(HIER) | Info | MSDS |
|
To view list prices or to place an online order, please Login