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Parathyroid Hormone Primary Antibodies

Parathyroid Hormone

Human parathyroid adenoma stained with NCL-L-PTH-488.  Note cytoplasmic and membranous staining in tumour cells.
Human parathyroid adenoma stained with NCL-L-PTH-488. Note cytoplasmic and membranous staining in tumour cells.

Antigen Background

The parathyroid glands are small, oval, endocrine glands closely associated with the thyroid gland. The parathyroid glands regulate serum calcium and phosphate levels via parathyroid hormone (parathormone). Parathyroid hormone raises serum calcium levels directly, by increasing the rate of osteoclastic reabsorption and promoting breakdown of the bone matrix, and indirectly, by increasing the renal tubular reabsorption of calcium ions and inhibiting the reabsorption of phosphate ions from the glomerular filtrate, and finally, by promoting the absorption of calcium from the small intestine. Parathyroid hormone is the most important regulator of blood calcium levels and is essential to life, whereas calcitonin appears only to provide a complementary mechanism for fine adjustment. Chief cells are the most abundant cells in the parathyroid gland and are responsible for the secretion of parathyroid hormone.

Parathyroid Hormone is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.


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CLONE: 105G7

Material with code "PTH" is discontinued , possible alternatives:

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Code Name Configuration Use Datasheet MSDS Qty
PTH-488-L-CE 1ml NCL-L-PTH-488 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
PTH-488-U 1ml NCL-PTH-488 US IVD Lyophilised Concentrated Monoclonal Antibody P Info MSDS
PTH-488-S 0.1ml NCL-PTH-488 Lyophilised Concentrated Monoclonal Antibody P Info MSDS
PTH-488 1ml NCL-PTH-488 Lyophilised Concentrated Monoclonal Antibody P Info MSDS