Napsin A has a specific function in normal alveolar epithelium and is proposed to play a role in the proteolytic processing of surfactant precursors.
Napsin A is reported to be predominantly expressed in lamellar bodies of type II pneumocytes, secondary lysosomes of alveolar macrophages, respiratory epithelium of terminal and respiratory bronchioles, plasma cells, within a subset of lymphocytes in normal lung, as well as in epithelial cells of renal tubules in normal kidney and is weakly expressed in normal spleen.
Studies have reported that Napsin A is expressed in 90 percent of primary lung adenocarcinomas.
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|PA0064-CN||Bond Prim Ab Napsin A (IP64) 7mL (China)|