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Epidermal Growth Factor Receptor Primary Antibodies

Epidermal Growth Factor Receptor Novocastra

Human squamous cell carcinoma of breast: immunohistochemical staining for epidermal growth factor receptor using NCL-L-EGFR-384. Note intense membrane staining of tumor  cells. Paraffin section.
Human squamous cell carcinoma of breast: immunohistochemical staining for epidermal growth factor receptor using NCL-L-EGFR-384. Note intense membrane staining of tumor cells. Paraffin section.

Antigen Background

Epidermal growth factor receptor (EGFR) is a transmembrane protein receptor of 170 kD with tyrosine kinase activity. Increased levels of EGFR are reported to be linked with malignant transformation of squamous cells eg in squamous cell carcinoma of the lung, head, neck, skin, cervix and esophagus. EGFR may also play a role in the development and progression of hepatocellular carcinomas where recurrence rates are higher in EGFR-positive cases. This correlation has similarly been reported in colorectal cancers where EGFR, produced by tumor cells, plays an important role in the invasiveness and proliferation of colorectal cancers. The majority of published studies of EGFR expression in human breast cancer has similarly shown an association with EGFR expression where it is inversely related to estrogen receptor status.

Product Specific Information

Clone EGFR.25 is raised to the cytoplasmic domain of the EGFR molecule whereas clone EGFR.113 is raised to the extracellular domain.


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Material with code "EGFR" is discontinued , possible alternatives:

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Code Name Qty
KCN-10702 EGFR (7p11) / SE 7

CLONE: EGFR.113

Material with code "EGFR" is discontinued , possible alternatives:

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Code Name Configuration Use Datasheet MSDS Qty
EGFR-L 1ml NCL-L-EGFR Liquid Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
EGFR-L-CE 1ml NCL-L-EGFR Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
EGFR-CE 1ml NCL-EGFR Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
EGFR-CE-S 0.1ml NCL-EGFR Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
EGFR 1ml NCL-EGFR Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS

CLONE: EGFR.25

Material with code "EGFR" is discontinued , possible alternatives:

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Code Name Configuration Use Datasheet MSDS Qty
EGFR-384-L 1ml NCL-L-EGFR-384 Liquid Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
EGFR-384-L-CE 1ml NCL-L-EGFR-384 Liquid Concentrated Monoclonal Antibody P(HIER) Info MSDS
EGFR-384 1ml NCL-EGFR-384 Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
EGFR-384-CE-S 0.1ml NCL-EGFR-384 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
EGFR-384-S 0.1ml NCL-EGFR-384 Lyophilised Concentrated Monoclonal Antibody F, P(HIER) Info MSDS
EGFR-384-CE 1ml NCL-EGFR-384 Lyophilised Concentrated Monoclonal Antibody P(HIER) Info MSDS
EGFR-384-R-7-CE 7ml RTU-EGFR-384 Ready to Use Monoclonal Antibody P(HIER) Info
EGFR-384-R-7 7ml RTU-EGFR-384 Ready to Use Monoclonal Antibody F, P(HIER) Info