The CD57 glycoprotein, also known as HNK-1, has a molecular weight of 110 kD.It is found on a subset of mononuclear cells with natural killer activity and on neuroectodermal cells expressing myelin-associated glycoprotein. Many cells which co-express CD57 and CD8 proteins are a subset of suppressor/cytotoxic T cells. These cells play a role in the rejection of grafts in acute graft versus host disease. The CD57 molecule is not expressed on erythrocytes or platelets.
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Enzyme pretreatment may enhance staining in some cases.
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|PA0443||7ml CD57 Bond RTU Prim|