CD141 (Thrombomodulin) Novocastra
Thrombomodulin is a transmembrane glycoprotein of 75 kD which can accelerate the activation of protein C. Activated protein C functions as an anticoagulant by combining with protein S to inactivate factors Va and VIIIa of the blood coagulation pathway and by binding thrombin. Several factorsregulate thrombomodulin expression. Downregulation of thrombomodulin may be induced by the cytokine interleukin-1, tumor necrosis factor and endotoxin. Agents which increase cyclic AMP such as forskolin may upregulate thrombomodulin activity in endothelial cells. Thrombomodulin has been identified within a number of normal tissues. These include the lining cells of arteries, veins, capillaries and the lymphatics as well as mesothelial cells, meningeal lining cells, synovial cells, syncytiotrophoblasts, megakaryocytes and platelets.
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|CD141-L-U||1ml NCL-L-CD141||Liquid Concentrated Monoclonal Antibody||P(HIER)||Info||MSDS||
|CD141||1ml NCL-CD141||Lyophilised Concentrated Monoclonal Antibody||F, P(HIER)||Info||MSDS||
|CD141-U||1ml NCL-CD141 US IVD||Lyophilised Concentrated Monoclonal Antibody||F, P(HIER)||MSDS||
|CD141-S||0.1ml NCL-CD141||Lyophilised Concentrated Monoclonal Antibody||F, P(HIER)||Info||MSDS||